Steady-State Piperacillin Concentrations in the Proximity of an Orthopedic Implant: A Microdialysis Porcine Study.
implants
microdialysis
osteomyelitis
piperacillin
steady state
tazobactam
Journal
Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404
Informations de publication
Date de publication:
20 Mar 2023
20 Mar 2023
Historique:
received:
24
02
2023
revised:
14
03
2023
accepted:
17
03
2023
medline:
30
3
2023
entrez:
29
3
2023
pubmed:
30
3
2023
Statut:
epublish
Résumé
Implant-associated osteomyelitis is one of the most feared complications following orthopedic surgery. Although the risk is low, sufficient antibiotic protection of the implant surface is important. The aim of this study was to assess steady-state piperacillin concentrations in the proximity of an orthopedic implant. Time above the minimal inhibitory concentration (
Identifiants
pubmed: 36978481
pii: antibiotics12030615
doi: 10.3390/antibiotics12030615
pmc: PMC10045023
pii:
doi:
Types de publication
Journal Article
Langues
eng
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