THINC-Integrated Tool (THINC-it): A Brief Measurement of Changes in Cognitive Functioning and Its Correlation with the Life Quality of Patients with Schizophrenia and Related Disorders-A Pilot Study.
RDoC
cognition
cognitive functions
depression
domains
function
measurement-based care
patient-reported outcomes
quality of life
schizophrenia
Journal
Brain sciences
ISSN: 2076-3425
Titre abrégé: Brain Sci
Pays: Switzerland
ID NLM: 101598646
Informations de publication
Date de publication:
24 Feb 2023
24 Feb 2023
Historique:
received:
20
12
2022
revised:
30
01
2023
accepted:
22
02
2023
medline:
30
3
2023
entrez:
29
3
2023
pubmed:
30
3
2023
Statut:
epublish
Résumé
This pilot study aimed to assess patients' cognitive functioning with the Polish version of the THINC-it tool and to analyze its association with self-reported quality of life (QOL). Twenty-one patients (mean age: 37.8 ± 10.4) were assessed at baseline and after six weeks of a standard therapeutic outpatient program. Participants completed the World Health Organization QOL Questionnaire (WHOQOL-BREF) and the THINC-it tool at both visits. The tool consists of tasks evaluating working memory (SYMBOL CHECK), attention (SPOTTER), executive functions (TRIALS), and cognitive skills (CODEBREAKER). During the second visit, patients showed significant improvements in mean latency of correct responses of SPOTTER: These results suggest the THINC-it tool has utility as a cognitive measure in adults with schizophrenia in both clinical and research settings.
Sections du résumé
BACKGROUND
BACKGROUND
This pilot study aimed to assess patients' cognitive functioning with the Polish version of the THINC-it tool and to analyze its association with self-reported quality of life (QOL).
METHODS
METHODS
Twenty-one patients (mean age: 37.8 ± 10.4) were assessed at baseline and after six weeks of a standard therapeutic outpatient program. Participants completed the World Health Organization QOL Questionnaire (WHOQOL-BREF) and the THINC-it tool at both visits. The tool consists of tasks evaluating working memory (SYMBOL CHECK), attention (SPOTTER), executive functions (TRIALS), and cognitive skills (CODEBREAKER).
RESULTS
RESULTS
During the second visit, patients showed significant improvements in mean latency of correct responses of SPOTTER:
CONCLUSIONS
CONCLUSIONS
These results suggest the THINC-it tool has utility as a cognitive measure in adults with schizophrenia in both clinical and research settings.
Identifiants
pubmed: 36979199
pii: brainsci13030389
doi: 10.3390/brainsci13030389
pmc: PMC10046273
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Neuropsychiatr Dis Treat. 2018 Oct 29;14:2861-2877
pubmed: 30464471
J Affect Disord. 2018 Oct 1;238:228-232
pubmed: 29886204
Int J Ment Health Nurs. 2004 Dec;13(4):282-91
pubmed: 15660598
Schizophr Bull. 1997;23(3):437-58
pubmed: 9327508
Front Hum Neurosci. 2010 Apr 26;4:32
pubmed: 20461148
Schizophr Bull. 2012 Nov;38(6):1297-307
pubmed: 22080494
J Rehabil Res Dev. 2006 Jan-Feb;43(1):73-82
pubmed: 16847773
Int J Neuropsychopharmacol. 2016 May 26;19(10):
pubmed: 27231256
Neuroscientist. 2012 Apr;18(2):180-200
pubmed: 21531988
J Clin Psychiatry. 2017 Jul;78(7):873-881
pubmed: 28858441
Prog Neuropsychopharmacol Biol Psychiatry. 2005 Feb;29(2):239-44
pubmed: 15694230
Lancet. 2020 Dec 5;396(10265):1841-1856
pubmed: 33278937
Int J Mol Sci. 2021 Sep 14;22(18):
pubmed: 34576069
Aust N Z J Psychiatry. 2008 Jun;42(6):496-504
pubmed: 18465376
J Affect Disord. 2018 Jan 1;225:559-562
pubmed: 28869910
Schizophr Bull. 1999;25(2):291-307
pubmed: 10416732
J Psychiatry Neurosci. 2000 Mar;25(2):117-24
pubmed: 10740985
Brain Sci. 2022 Jan 18;12(2):
pubmed: 35203893
Psychiatry Res. 1997 Oct 10;72(3):161-6
pubmed: 9406905
Psychiatry Res. 2011 Jun 30;192(3):160-6
pubmed: 21543191
Front Psychiatry. 2021 Nov 23;12:763603
pubmed: 34887790
Acta Psychiatr Scand. 1996 Aug;94(2):118-24
pubmed: 8883573
Depress Anxiety. 2013 Jun;30(6):515-27
pubmed: 23468126
Scand J Pain. 2017 Apr;15:62-67
pubmed: 28850348
Front Psychiatry. 2020 Jun 24;11:546
pubmed: 32670103
Schizophr Res. 2014 Feb;152(2-3):339-43
pubmed: 24439000
Eur Neuropsychopharmacol. 2021 Dec;53:34-46
pubmed: 34375789
J Clin Psychiatry. 2018 Nov 20;80(1):
pubmed: 30549482
J Am Geriatr Soc. 2005 Apr;53(4):695-9
pubmed: 15817019
Soc Psychiatry Psychiatr Epidemiol. 2002 Nov;37(11):510-8
pubmed: 12395140
J Affect Disord. 2021 Mar 1;282:448-453
pubmed: 33422821
Brain Sci. 2022 Nov 18;12(11):
pubmed: 36421896
Neuropsychiatr Dis Treat. 2020 Oct 21;16:2419-2428
pubmed: 33116541
Brain Sci. 2022 Mar 21;12(3):
pubmed: 35326369
Behav Modif. 1996 Apr;20(2):139-69
pubmed: 8934864
Br J Psychiatry. 2017 Mar;210(3):216-222
pubmed: 28153927
Arch Gen Psychiatry. 1991 Mar;48(3):239-46
pubmed: 1671741
Front Psychiatry. 2021 Jul 28;12:696903
pubmed: 34393857
Schizophr Res. 2008 Feb;99(1-3):176-81
pubmed: 17681756
Am J Psychiatry. 2007 Dec;164(12):1791-802
pubmed: 18056233
J Psychiatr Res. 2012 Oct;46(10):1249-56
pubmed: 22790253
Schizophr Bull. 1997;23(1):19-28
pubmed: 9050110
Int J Methods Psychiatr Res. 2018 Sep;27(3):e1736
pubmed: 30088298