Regulation of ErbB Receptors by the Ca
ErbB receptors
calcineurin
calcium
calmodulin
calmodulin-dependent kinases
epidermal growth factor receptor
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
22 Feb 2023
22 Feb 2023
Historique:
received:
15
01
2023
revised:
17
02
2023
accepted:
19
02
2023
medline:
30
3
2023
entrez:
29
3
2023
pubmed:
30
3
2023
Statut:
epublish
Résumé
Overexpression and mutations of the epidermal growth factor receptor (EGFR/ErbB1/HER1) and other tyrosine kinase receptors of the ErbB family (ErbB2/HER2, ErbB3/HER3 and ErbB4/HER4) play an essential role in enhancing the proliferation, the migratory capacity and invasiveness of many tumor cells, leading to cancer progression and increased malignancy. To understand these cellular processes in detail is essential to understand at a molecular level the signaling pathways and regulatory mechanisms controlling these receptors. In this regard, calmodulin (CaM) is a Ca
Identifiants
pubmed: 36979639
pii: biomedicines11030661
doi: 10.3390/biomedicines11030661
pmc: PMC10045772
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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