Characterization of Muscle Weakness Due to Myasthenia Gravis Using Shear Wave Elastography.

biceps brachii muscle stiffness muscle weakness myasthenia gravis shear wave elastography skeletal muscle mechanics surface electromyography

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
15 Mar 2023
Historique:
received: 06 02 2023
revised: 05 03 2023
accepted: 14 03 2023
medline: 30 3 2023
entrez: 29 3 2023
pubmed: 30 3 2023
Statut: epublish

Résumé

Myasthenia gravis (MG) is often accompanied with muscle weakness; however, little is known about mechanical adaptions of the affected muscles. As the latter can be assessed using ultrasound shear wave elastography (SWE), this study characterizes the biceps brachii muscle of 11 patients with MG and compares them with that of 14 healthy volunteers. Simultaneous SWE, elbow torque and surface electromyography measurements were performed during rest, maximal voluntary contraction (MVC) and submaximal isometric contractions (up to 25%, 50% and 75% MVC) at different elbow angles from flexion to extension. We found that, with increasing elbow angle, maximum elbow torque decreased (

Identifiants

pubmed: 36980415
pii: diagnostics13061108
doi: 10.3390/diagnostics13061108
pmc: PMC10047651
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Deutsche Forschungsgemeinschaft
ID : GRK 2198 - 277536708
Organisme : Federal Ministry of Education and Research
ID : 01EC1907B
Organisme : Deutsche Forschungsgemeinschaft
ID : 512689491

Références

Neurology. 2000 Jul 12;55(1):16-23
pubmed: 10891897
Clin Biomech (Bristol, Avon). 2014 Sep;29(8):943-9
pubmed: 25001327
Eur J Appl Physiol Occup Physiol. 1995;70(5):421-6
pubmed: 7671877
J Biomech. 2019 Aug 27;93:111-117
pubmed: 31280899
J Biomech. 2013 Sep 27;46(14):2381-7
pubmed: 23953670
Neuromuscul Disord. 2020 Aug;30(8):631-639
pubmed: 32718868
J Transl Med. 2021 Dec 20;19(1):516
pubmed: 34930325
Clin Biomech (Bristol, Avon). 2015 Jan;30(1):22-7
pubmed: 25483294
Eur J Appl Physiol. 2018 Mar;118(3):585-593
pubmed: 29327169
J Biomech. 2019 Sep 20;94:115-122
pubmed: 31376979
Neurology. 1983 Oct;33(10):1316-21
pubmed: 6684226
J Appl Physiol (1985). 2020 Jan 1;128(1):8-16
pubmed: 31556833
J Biomech. 2003 Nov;36(11):1713-8
pubmed: 14522213
J Physiol. 1966 May;184(1):170-92
pubmed: 5921536
J Biomech. 1988;21(3):183-90
pubmed: 3379078
Eur J Appl Physiol. 2016 Apr;116(4):823-30
pubmed: 26874517
Clin Imaging. 2019 Jan - Feb;53:35-42
pubmed: 30308432
J Appl Physiol (1985). 2012 Nov;113(9):1353-61
pubmed: 22984244
J Electromyogr Kinesiol. 2013 Oct;23(5):1199-205
pubmed: 23837929
J Electromyogr Kinesiol. 2000 Oct;10(5):361-74
pubmed: 11018445
Diagnostics (Basel). 2021 Jan 23;11(2):
pubmed: 33498617
Healthcare (Basel). 2021 Dec 14;9(12):
pubmed: 34946459
Clin Imaging. 2016 Nov - Dec;40(6):1075-1080
pubmed: 27408992
Am J Phys Med Rehabil. 2005 Aug;84(8):627-38
pubmed: 16034233
Neurol Ther. 2023 Feb;12(1):107-128
pubmed: 36322146
Neurol Clin. 2018 May;36(2):339-353
pubmed: 29655453
J Mech Behav Biomed Mater. 2023 Jan;137:105543
pubmed: 36371993
Eur Radiol. 2021 May;31(5):3187-3194
pubmed: 33052467
J Acoust Soc Am. 2022 Apr;151(4):2403
pubmed: 35461517
J Biomech. 2012 Apr 5;45(6):978-84
pubmed: 22326058
PM R. 2010 May;2(5):399-405
pubmed: 20656621
Aging Clin Exp Res. 2019 Dec;31(12):1755-1763
pubmed: 30762201
J Neuromuscul Dis. 2015;2(1):73-85
pubmed: 28198707
J Electromyogr Kinesiol. 2015 Aug;25(4):703-8
pubmed: 25956546
Clin Exp Immunol. 2014 Mar;175(3):408-18
pubmed: 24117026
J Mech Behav Biomed Mater. 2018 Aug;84:208-216
pubmed: 29793158
Neurol Sci. 2021 Oct;42(10):4155-4162
pubmed: 33538915
J Electromyogr Kinesiol. 2017 Oct;36:49-55
pubmed: 28735102
Clin Biomech (Bristol, Avon). 2001 Feb;16(2):87-101
pubmed: 11222927
J Electromyogr Kinesiol. 2020 Oct;54:102440
pubmed: 32763743

Auteurs

Manuela Zimmer (M)

Institute of Structural Mechanics and Dynamics in Aerospace Engineering, University of Stuttgart, Pfaffenwaldring 27, 70569 Stuttgart, Germany.

Benedict Kleiser (B)

Department of Epileptology, Hertie-Institute for Clinical Brain Research, University of Tübingen, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany.

Justus Marquetand (J)

Department of Epileptology, Hertie-Institute for Clinical Brain Research, University of Tübingen, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany.
Department of Neural Dynamics and Magnetoencephalography, Hertie-Institute for Clinical Brain Research, University of Tübingen, Otfried-Müller-Str. 25, 72076 Tübingen, Germany.
MEG-Center, University of Tübingen, Otfried-Müller-Str. 47, 72076 Tübingen, Germany.

Filiz Ates (F)

Institute of Structural Mechanics and Dynamics in Aerospace Engineering, University of Stuttgart, Pfaffenwaldring 27, 70569 Stuttgart, Germany.

Classifications MeSH