Small Extracellular Vesicles (sEVs) Biogenesis Molecular Players Are Associated with Clinical Outcome of Colorectal Cancer Patients.
colorectal cancer
exosomes
expression
sEVs
survival
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
09 Mar 2023
09 Mar 2023
Historique:
received:
21
01
2023
revised:
01
03
2023
accepted:
04
03
2023
medline:
30
3
2023
entrez:
29
3
2023
pubmed:
30
3
2023
Statut:
epublish
Résumé
A growing number of studies have shed light on the role of small extracellular vesicles (sEVs), including exosomes, in colorectal cancer (CRC). Available data regarding the clinical significance of molecular players in CRC, implicated in sEVs biogenesis, is limited. In this study, we assessed the expression of the most important genes which are implicated in sEVs biogenesis and their association with sEVs plasma levels, investigated with a double sandwich ELISA assay, as well as with the clinical outcome of patients with CRC. Our study shows that
Identifiants
pubmed: 36980570
pii: cancers15061685
doi: 10.3390/cancers15061685
pmc: PMC10046180
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : EOGE Oncological Funds, Greece
ID : Exosomes project
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