Epidemiological Characteristics of Cancer Patients Attending at Felege Hiwot Referral Hospital, Northwest Ethiopia.
Amhara region
Ethiopia
cancer hot pots
epidemiology
Journal
International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455
Informations de publication
Date de publication:
22 03 2023
22 03 2023
Historique:
received:
14
02
2023
revised:
13
03
2023
accepted:
14
03
2023
medline:
30
3
2023
entrez:
29
3
2023
pubmed:
30
3
2023
Statut:
epublish
Résumé
Cancer has become a public health problem and a challenge in developing countries, including Ethiopia. There is scanty local data on cancer epidemiology in Amhara region, Ethiopia. Thus, this study aimed to describe epidemiological characteristics of cancer patients attending Felege Hiwot Referral Hospital. This study was based on a patient cancer registry that took place in Bahir Dar Felege Hiwot Referral Hospital, Amhara Regional State, Ethiopia. It is the main referral hospital in the Amhara region, and serves more than 5 million people. The hospital has units including oncology for follow-up health care services. All confirmed cancer patients attending oncology units from July 2017 to June 2019 were included in the study. Global Moran's I statistic was employed to assess spatial heterogeneity of cancer cases across districts. Getis-Ord Gi* statistics was performed to identify hot spot districts with high numbers of cancer cases. In a two-year period, a total of 1888 confirmed cancer patients were registered. There was a significant variation of cancer patients between females (60.8% 95%CI 58.5 to 63.0%) and males (39.3% 95%CI 37.0 to 41.5%). The first three most frequent cancer types seen were breast (19.4%) and cervical cancer (12.9%), and lymphoma (15.7%). Breast and cervical cancer and lymphoma were the first three cancers type among women, whereas lymphoma, sarcoma, and lung cancer were the three most common cancer among men. Spatially, cancer cases were non-random in the study area (global Moran's I = 0.25, z-score = 5.6, We found that there is a variation in the cancer types with sex. This study provides an insight for further exploration of environmental and occupational exposure related factors for cancer to guide future cancer prevention and control programs. The current study also calls for expansion of cancer registry sites, including in rural areas in the region.
Sections du résumé
BACKGROUND
Cancer has become a public health problem and a challenge in developing countries, including Ethiopia. There is scanty local data on cancer epidemiology in Amhara region, Ethiopia. Thus, this study aimed to describe epidemiological characteristics of cancer patients attending Felege Hiwot Referral Hospital.
METHODS
This study was based on a patient cancer registry that took place in Bahir Dar Felege Hiwot Referral Hospital, Amhara Regional State, Ethiopia. It is the main referral hospital in the Amhara region, and serves more than 5 million people. The hospital has units including oncology for follow-up health care services. All confirmed cancer patients attending oncology units from July 2017 to June 2019 were included in the study. Global Moran's I statistic was employed to assess spatial heterogeneity of cancer cases across districts. Getis-Ord Gi* statistics was performed to identify hot spot districts with high numbers of cancer cases.
RESULTS
In a two-year period, a total of 1888 confirmed cancer patients were registered. There was a significant variation of cancer patients between females (60.8% 95%CI 58.5 to 63.0%) and males (39.3% 95%CI 37.0 to 41.5%). The first three most frequent cancer types seen were breast (19.4%) and cervical cancer (12.9%), and lymphoma (15.7%). Breast and cervical cancer and lymphoma were the first three cancers type among women, whereas lymphoma, sarcoma, and lung cancer were the three most common cancer among men. Spatially, cancer cases were non-random in the study area (global Moran's I = 0.25, z-score = 5.6,
CONCLUSIONS
We found that there is a variation in the cancer types with sex. This study provides an insight for further exploration of environmental and occupational exposure related factors for cancer to guide future cancer prevention and control programs. The current study also calls for expansion of cancer registry sites, including in rural areas in the region.
Identifiants
pubmed: 36982127
pii: ijerph20065218
doi: 10.3390/ijerph20065218
pmc: PMC10049658
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
J Glob Oncol. 2018 Sep;4:1-11
pubmed: 30241262
JAMA Oncol. 2017 Apr 01;3(4):524-548
pubmed: 27918777
J Cancer Epidemiol. 2017;2017:8312064
pubmed: 28321255
Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):16-27
pubmed: 26667886
JAMA Oncol. 2018 Nov 1;4(11):1553-1568
pubmed: 29860482
Cancer Epidemiol Biomarkers Prev. 2017 Apr;26(4):444-457
pubmed: 28223433
Environ Pollut. 2017 Dec;231(Pt 1):319-328
pubmed: 28810201
Cancer Epidemiol Biomarkers Prev. 2014 Jun;23(6):953-66
pubmed: 24700176
Asian Pac J Cancer Prev. 2018 Feb 26;19(2):319-324
pubmed: 29479954
Sci Rep. 2016 May 17;6:25768
pubmed: 27185567
Psychooncology. 2017 Sep;26(9):1263-1269
pubmed: 28872742
Int J Environ Res Public Health. 2020 Jul 24;17(15):
pubmed: 32722265
Int J Environ Res Public Health. 2022 Oct 04;19(19):
pubmed: 36232004
Int J Environ Res Public Health. 2023 Feb 08;20(4):
pubmed: 36833684
Cancer Epidemiol Biomarkers Prev. 2019 May;28(5):890-899
pubmed: 30944147
Cancer Epidemiol Biomarkers Prev. 2009 Apr;18(4):1174-82
pubmed: 19293308
Cancer Epidemiol. 2018 Apr;53:93-98
pubmed: 29414637
Ann Oncol. 2013 Sep;24(9):2245-55
pubmed: 23788758
Lancet. 2010 Aug 28;376(9742):717-29
pubmed: 20673583
BMC Cancer. 2019 Apr 25;19(1):393
pubmed: 31023270
Breast J. 2019 Jul;25(4):795-797
pubmed: 31074067
BMC Cancer. 2017 Jun 16;17(1):421
pubmed: 28622762
Lancet. 2017 Feb 25;389(10071):861-870
pubmed: 27814963
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Cancer Res Treat. 2013 Sep;45(3):226-33
pubmed: 24155682
J Glob Oncol. 2019 Nov;5:1-8
pubmed: 31834831
Cancer Epidemiol. 2017 Oct;50(Pt A):46-52
pubmed: 28803070
Asian Pac J Cancer Prev. 2014;15(21):9433-7
pubmed: 25422237
J Glob Oncol. 2018 Dec;4:1-11
pubmed: 30582432