Extracellular Matrix Disorganization and Sarcolemmal Alterations in COL6-Related Myopathy Patients with New Variants of COL6 Genes.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
14 Mar 2023
Historique:
received: 30 11 2022
revised: 08 03 2023
accepted: 09 03 2023
medline: 30 3 2023
entrez: 29 3 2023
pubmed: 30 3 2023
Statut: epublish

Résumé

Collagen VI is a heterotrimeric protein expressed in several tissues and involved in the maintenance of cell integrity. It localizes at the cell surface, creating a microfilamentous network that links the cytoskeleton to the extracellular matrix. The heterotrimer consists of three chains encoded by

Identifiants

pubmed: 36982625
pii: ijms24065551
doi: 10.3390/ijms24065551
pmc: PMC10059973
pii:
doi:

Substances chimiques

Collagen Type VI 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Italian Ministry of Health, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico
ID : Ricerca Corrente 2023 to GPC

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Auteurs

Simona Zanotti (S)

Neuromuscular and Rare Diseases Unit, Department of Neuroscience, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Francesca Magri (F)

Neurology Unit, Department of Neuroscience Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Sabrina Salani (S)

Neurology Unit, Department of Neuroscience Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Laura Napoli (L)

Neuromuscular and Rare Diseases Unit, Department of Neuroscience, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Michela Ripolone (M)

Neuromuscular and Rare Diseases Unit, Department of Neuroscience, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Dario Ronchi (D)

Dino Ferrari Centre, Department of Pathophysiology and Transplantation (DEPT), University of Milan, 20122 Milan, Italy.

Francesco Fortunato (F)

Dino Ferrari Centre, Department of Pathophysiology and Transplantation (DEPT), University of Milan, 20122 Milan, Italy.

Patrizia Ciscato (P)

Neuromuscular and Rare Diseases Unit, Department of Neuroscience, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Daniele Velardo (D)

Neuromuscular and Rare Diseases Unit, Department of Neuroscience, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Maria Grazia D'Angelo (MG)

IRCCS Eugenio Medea, Bosisio Parini, 23842 Lecco, Italy.

Francesca Gualandi (F)

Medical Genetics Unit, Department of Medical Science, University of Ferrara, 44121 Ferrara, Italy.

Vincenzo Nigro (V)

Dipartimento di Medicina di Precisione, "Luigi Vanvitelli" University of Campania and Telethon Institute of Genetics and Medicine (TIGEM), 81100 Naples, Italy.

Monica Sciacco (M)

Neuromuscular and Rare Diseases Unit, Department of Neuroscience, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Neurology Unit, Department of Neuroscience Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Stefania Corti (S)

Neurology Unit, Department of Neuroscience Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Dino Ferrari Centre, Department of Pathophysiology and Transplantation (DEPT), University of Milan, 20122 Milan, Italy.

Giacomo Pietro Comi (GP)

Neuromuscular and Rare Diseases Unit, Department of Neuroscience, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Dino Ferrari Centre, Department of Pathophysiology and Transplantation (DEPT), University of Milan, 20122 Milan, Italy.

Daniela Piga (D)

Neurology Unit, Department of Neuroscience Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

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Classifications MeSH