Cognitive Dysfunctions Measured with the MCCB in Deficit and Non-Deficit Schizophrenia.
MCCB
PANSS
cognitive functions
deficit schizophrenia
non-deficit schizophrenia
psychopathology
schizophrenia
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
14 Mar 2023
14 Mar 2023
Historique:
received:
31
12
2022
revised:
12
03
2023
accepted:
13
03
2023
medline:
30
3
2023
entrez:
29
3
2023
pubmed:
30
3
2023
Statut:
epublish
Résumé
This study compared cognitive domains between deficit schizophrenia (DS) and non-deficit schizophrenia (NDS) patients and healthy controls (HC), analyzing relationships between psychopathological dimensions and cognitive domains. A total of 29 DS patients, 45 NDS patients, and 39 HC subjects participated. Cognitive domains were measured using the Measurement and Treatment Research to Improve Cognition in Schizophrenia Battery. Psychopathological symptoms were evaluated with the Positive and Negative Syndrome Scale. Clinical groups performed poorer than HC groups in regards to speed of processing, attention/vigilance, working memory, verbal and visual learning and memory, reasoning and problem solving, and social cognition. DS patients scored poorer than NDS patients in terms of all cognitive domains and the overall score, except for reasoning and problem solving. Positive, negative, disorganization, and resistance symptoms were related to cognitive functions only in NDS patients. Our findings suggest that the MCCB battery is sensitive to detecting cognitive dysfunctions in both deficit and non-deficit schizophrenia.
Identifiants
pubmed: 36983258
pii: jcm12062257
doi: 10.3390/jcm12062257
pmc: PMC10053076
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Pomeranian Medical University in Szczecin
ID : FSN-337-441 06/2016 and FNS-246-05/2017
Organisme : Faculty of Humanities at the University of Szczecin
ID : 504-442 3000-240-940/2015/2016
Organisme : Polish Minister of Science and Higher Education's program named "Regional Initiative of Excellence" 2019-2022
ID : 002/RID/2018/19
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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