The risk of fragment penetrating injury to the heart.

Depth of penetration Injury-risk curve Lamb heart Penetrating injury Secondary blast injury Survival analysis

Journal

Journal of the mechanical behavior of biomedical materials
ISSN: 1878-0180
Titre abrégé: J Mech Behav Biomed Mater
Pays: Netherlands
ID NLM: 101322406

Informations de publication

Date de publication:
05 2023
Historique:
received: 06 09 2022
revised: 24 02 2023
accepted: 10 03 2023
medline: 11 4 2023
pubmed: 30 3 2023
entrez: 29 3 2023
Statut: ppublish

Résumé

Injury due to the penetration of fragments into parts of the body has been the major cause of morbidity and mortality after an explosion. Penetrating injuries into the heart present very high mortality, yet the risk associated with such injuries has not been quantified. Quantifying this risk is key in the design of personal protection and the design of infrastructure. This study is the first quantitative assessment of cardiac penetrating injuries from energised fragments. Typical fragments (5-mm sphere, 0.78-g right-circular cylinder and 1.1-g chisel-nosed cylinder) were accelerated to a range of target striking velocities using a bespoke gas-gun system and impacted ventricular and atrial walls of lamb hearts. The severity of injury was shown to not depend on location (ventricular or atrial wall). The striking velocity with 50% probability of critical injury (Abbreviated Injury Scale (AIS) 5 score) ranged between 31 and 36 m/s across all 3 fragments used. These findings can help directly in reducing morbidity and mortality from explosive events as they can be implemented readily into models that aim to predict casualties in an explosive event, inform protocols for first responders, and improve design of infrastructure and personal protective equipment.

Identifiants

pubmed: 36989869
pii: S1751-6161(23)00129-7
doi: 10.1016/j.jmbbm.2023.105776
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

105776

Informations de copyright

Copyright © 2023. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Hirotaka Tsukada (H)

Department of Bioengineering, Imperial College London, UK.

Thuy-Tien N Nguyen (TN)

Department of Bioengineering, Imperial College London, UK.

John Breeze (J)

Department of Bioengineering, Imperial College London, UK; Royal Centre for Defence Medicine, Queen Elizabeth Hospital Birmingham, UK.

Spyros D Masouros (SD)

Department of Bioengineering, Imperial College London, UK. Electronic address: s.masouros04@imperial.ac.uk.

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Classifications MeSH