Vaccination of Zoo Birds against West Nile Virus-A Field Study.
Germany
West Nile virus (WNV)
inactivated vaccine
zoo bird
zoological garden
Journal
Vaccines
ISSN: 2076-393X
Titre abrégé: Vaccines (Basel)
Pays: Switzerland
ID NLM: 101629355
Informations de publication
Date de publication:
14 Mar 2023
14 Mar 2023
Historique:
received:
07
02
2023
revised:
07
03
2023
accepted:
10
03
2023
medline:
31
3
2023
entrez:
30
3
2023
pubmed:
31
3
2023
Statut:
epublish
Résumé
West Nile virus (WNV) is known to cause disease and death in humans and various animals worldwide. WNV has circulated in Germany since 2018. In 2020, four birds tested positive for the WNV genome at Zoopark Erfurt (Thuringia). Moreover, virus neutralization assays detected neutralizing antibodies (nAb) against WNV in 28 birds. In addition, nAb against WNV and Usutu virus (USUV) were found in 14 birds. To protect valuable animals and to reduce the risk of viral transmission from birds to humans, we performed a field study on WNV vaccination at the zoo. To conduct the study, 61 birds from the zoo were categorized into three groups and subjected to a vaccination regimen, where each bird received either 1.0 mL, 0.5 mL, or 0.3 mL of a commercial inactivated WNV vaccine three times. The vaccinations were administered at three-week intervals, or as per modified vaccination schedules. Furthermore, 52 birds served as non-vaccinated controls. Adverse vaccination reactions were absent. The greatest increase in nAb titres was observed in birds that received 1.0 mL of vaccine. However, pre-existing antibodies to WNV and USUV appeared to have a major effect on antibody development in all groups and in all bird species, whereas sex and age had no effect. After vaccination, no death was detected in vaccinated birds for more than 1 year.
Identifiants
pubmed: 36992236
pii: vaccines11030652
doi: 10.3390/vaccines11030652
pmc: PMC10058624
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Federal Ministry of Food and Agriculture
ID : 2819113919
Références
Trans R Soc Trop Med Hyg. 2015 Oct;109(10):609-18
pubmed: 26286946
J Zoo Wildl Med. 2007 Jun;38(2):240-4
pubmed: 17679507
Euro Surveill. 2019 May;24(21):
pubmed: 31138361
J Gen Virol. 1974 Apr;23(1):91-6
pubmed: 4833603
J Zoo Wildl Med. 2008 Dec;39(4):582-9
pubmed: 19110700
Emerg Infect Dis. 2002 Aug;8(8):820-6
pubmed: 12141968
PLoS One. 2012;7(2):e32604
pubmed: 22389712
Avian Dis. 2009 Sep;53(3):421-5
pubmed: 19848083
Vaccine. 2007 Mar 8;25(12):2325-30
pubmed: 17224209
J Wildl Dis. 2004 Jul;40(3):538-42
pubmed: 15465722
Int J Environ Res Public Health. 2013 Oct 11;10(10):4869-95
pubmed: 24157510
Curr Top Microbiol Immunol. 2002;267:271-308
pubmed: 12082994
J Zoo Wildl Med. 2005 Jun;36(2):257-64
pubmed: 17323567
Lancet Infect Dis. 2002 Sep;2(9):519-29
pubmed: 12206968
Annu Rev Entomol. 2008;53:61-81
pubmed: 17645411
Vet Res. 2014 Apr 07;45:41
pubmed: 24708385
Avian Dis. 2003 Jul-Sep;47(3):750-2
pubmed: 14562907
J Virol. 2003 Dec;77(24):12941-9
pubmed: 14645550
J Gen Virol. 1989 Jan;70 ( Pt 1):37-43
pubmed: 2543738
Vector Borne Zoonotic Dis. 2012 May;12(5):372-9
pubmed: 22217162
J Virol Methods. 2006 Sep;136(1-2):200-9
pubmed: 16806503
Vector Borne Zoonotic Dis. 2015 Aug;15(8):481-8
pubmed: 26273809
Clin Diagn Lab Immunol. 2005 May;12(5):665-7
pubmed: 15879030
Eur J Immunol. 2007 Jul;37(7):1845-54
pubmed: 17559174
Vector Borne Zoonotic Dis. 2011 Aug;11(8):1069-80
pubmed: 21438693
Science. 1999 Dec 17;286(5448):2333-7
pubmed: 10600742
Vector Borne Zoonotic Dis. 2010 Oct;10(7):639-47
pubmed: 20854016
Adv Virus Res. 1986;31:335-55
pubmed: 2428214
Vet Microbiol. 2013 Jan 25;161(3-4):263-73
pubmed: 22909991
J Virol. 2006 Dec;80(24):12149-59
pubmed: 17035317
Front Microbiol. 2022 Nov 09;13:1044316
pubmed: 36439823
Microorganisms. 2019 Jun 26;7(7):
pubmed: 31248051
Emerg Infect Dis. 2002 Dec;8(12):1392-7
pubmed: 12498653
J Zoo Wildl Med. 2007 Jun;38(2):337-40
pubmed: 17679521
Nat Protoc. 2017 Jun;12(6):1261-1276
pubmed: 28538739
Virology. 1996 Apr 15;218(2):417-21
pubmed: 8610471
Biomed Res Int. 2015;2015:376230
pubmed: 25866777
J Avian Med Surg. 2008 Sep;22(3):240-5
pubmed: 19014098
Antiviral Res. 2019 Feb;162:39-43
pubmed: 30550796
J Vet Diagn Invest. 2010 Sep;22(5):748-53
pubmed: 20807934
Viruses. 2019 Jul 23;11(7):
pubmed: 31340516
Emerg Infect Dis. 2002 Jul;8(7):652-6
pubmed: 12095429
Am J Trop Med Hyg. 2011 Sep;85(3):551-3
pubmed: 21896821
BMC Infect Dis. 2017 Sep 6;17(1):609
pubmed: 28877682
Parasit Vectors. 2021 Sep 6;14(1):449
pubmed: 34488835
Microorganisms. 2022 Apr 12;10(4):
pubmed: 35456857
Am J Vet Res. 2011 Aug;72(8):1065-70
pubmed: 21801064
Ecohealth. 2008 Sep;5(3):298-304
pubmed: 18677535
Euro Surveill. 2020 Oct;25(40):
pubmed: 33034280
Vet Microbiol. 2011 May 5;149(3-4):358-66
pubmed: 21276665
J Zoo Wildl Med. 2011 Sep;42(3):495-8
pubmed: 22950325
Virus Res. 2014 Aug 30;189:87-91
pubmed: 24874193
Transfus Med Hemother. 2022 Jun 20;49(4):192-204
pubmed: 36159956
J Med Entomol. 2019 Oct 28;56(6):1456-1462
pubmed: 31549728
Methods Mol Biol. 2016;1435:15-8
pubmed: 27188546
Euro Surveill. 2017 Jan 26;22(4):
pubmed: 28181903
Int J Environ Res Public Health. 2018 Jan 22;15(1):
pubmed: 29361762
Avian Dis. 2005 Jun;49(2):252-9
pubmed: 16094831
Expert Rev Vaccines. 2006 Aug;5(4):409-12
pubmed: 16989620
Euro Surveill. 2020 Nov;25(46):
pubmed: 33213686
Viruses. 2020 Jan 29;12(2):
pubmed: 32013152
Virology. 2015 Aug;482:67-71
pubmed: 25827530
Bioinformatics. 2018 Sep 15;34(18):3094-3100
pubmed: 29750242
J Med Entomol. 2019 Oct 28;56(6):1516-1521
pubmed: 31549724
Eur J Immunol. 2007 Jul;37(7):1855-63
pubmed: 17559175
Viruses. 2022 Jan 25;14(2):
pubmed: 35215837
Am J Trop Med Hyg. 2002 Jul;67(1):67-75
pubmed: 12363067
Emerg Infect Dis. 2003 Mar;9(3):311-22
pubmed: 12643825
J Zoo Wildl Med. 2009 Jun;40(2):263-71
pubmed: 19569472
Transbound Emerg Dis. 2022 Mar;69(2):776-792
pubmed: 33655706
J Hyg (Lond). 1972 Dec;70(4):611-7
pubmed: 4509639