The effect of different doses of vitamin D on the prognosis of patients undergoing carpal tunnel syndrome surgery.

Boston functional scale Boston severity scale carpal tunnel syndrome pain vitamin D

Journal

Journal of family medicine and primary care
ISSN: 2249-4863
Titre abrégé: J Family Med Prim Care
Pays: India
ID NLM: 101610082

Informations de publication

Date de publication:
Nov 2022
Historique:
received: 31 01 2022
revised: 24 04 2022
accepted: 17 05 2022
medline: 31 3 2023
entrez: 30 3 2023
pubmed: 31 3 2023
Statut: ppublish

Résumé

Vitamin D accelerates myelin repair and recovery after nerve damage. This study aimed to evaluate the effect of vitamin D on the prognosis of patients with carpal tunnel syndrome (CTS). A randomized clinical trial was conducted in the orthopedic ward of Golestan and Imam Khomeini hospitals in Ahvaz for 2 years (from October 2018 to October 2020). Patients were divided into three groups: the first group received 1,000 units of vitamin D daily, the second group received 4,000 units of vitamin D per week for the first 4-6 weeks and then 2,000 units per month, and the third group received no vitamin D supplementation. The results were compared before and after 6 months between the study groups. A total of 105 patients were included in the study, who were divided into three groups. The mean age of the patients was 39.24 ± 7.01 years (25-52 years). The mean level of the vitamin D in the control group was 25.40 ± 8.37 ng/mL, the group receiving 1,000 units/day was 26.71 ± 8.70 ng/mL, and the group receiving 50,000 units per week was 26.17 ± 8.63 ng/mL. The mean values of preoperative pain intensity, symptom severity, and functional status were almost the same in the three groups. These values were reduced after surgery in the two groups receiving the drug compared to the control group. The findings of the study showed that the administration of vitamin D supplementation in patients with CTS can significantly improve the postoperative symptoms of patients who underwent tendon release surgery and further improve the severity of symptoms and dysfunction of patients.

Sections du résumé

Background and Objective UNASSIGNED
Vitamin D accelerates myelin repair and recovery after nerve damage. This study aimed to evaluate the effect of vitamin D on the prognosis of patients with carpal tunnel syndrome (CTS).
Methods UNASSIGNED
A randomized clinical trial was conducted in the orthopedic ward of Golestan and Imam Khomeini hospitals in Ahvaz for 2 years (from October 2018 to October 2020). Patients were divided into three groups: the first group received 1,000 units of vitamin D daily, the second group received 4,000 units of vitamin D per week for the first 4-6 weeks and then 2,000 units per month, and the third group received no vitamin D supplementation. The results were compared before and after 6 months between the study groups.
Results UNASSIGNED
A total of 105 patients were included in the study, who were divided into three groups. The mean age of the patients was 39.24 ± 7.01 years (25-52 years). The mean level of the vitamin D in the control group was 25.40 ± 8.37 ng/mL, the group receiving 1,000 units/day was 26.71 ± 8.70 ng/mL, and the group receiving 50,000 units per week was 26.17 ± 8.63 ng/mL. The mean values of preoperative pain intensity, symptom severity, and functional status were almost the same in the three groups. These values were reduced after surgery in the two groups receiving the drug compared to the control group.
Conclusions UNASSIGNED
The findings of the study showed that the administration of vitamin D supplementation in patients with CTS can significantly improve the postoperative symptoms of patients who underwent tendon release surgery and further improve the severity of symptoms and dysfunction of patients.

Identifiants

pubmed: 36993071
doi: 10.4103/jfmpc.jfmpc_252_22
pii: JFMPC-11-6837
pmc: PMC10041256
doi:

Types de publication

Journal Article

Langues

eng

Pagination

6837-6842

Informations de copyright

Copyright: © 2022 Journal of Family Medicine and Primary Care.

Déclaration de conflit d'intérêts

There are no conflicts of interest.

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Auteurs

Karim Noorizadeh (K)

Department Orthopedic, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Seyed Mohammad Mohammadi (SM)

Department Orthopedic, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Mozhgan Seifi (M)

Department Orthopedic, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Mohammad Saeed Moradi (MS)

Department Orthopedic, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Hanoon Sadoni (H)

Department Orthopedic, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Classifications MeSH