Penicillin-binding protein redundancy in
Bacillus
activity-based probes
cell division
pH regulation
penicillin-binding proteins
Journal
bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187
Informations de publication
Date de publication:
20 Mar 2023
20 Mar 2023
Historique:
pubmed:
31
3
2023
medline:
31
3
2023
entrez:
30
3
2023
Statut:
epublish
Résumé
Penicillin-binding proteins (PBPs) play critical roles in cell wall construction, cell shape, and bacterial replication. Bacteria maintain a diversity of PBPs, indicating that despite their apparent functional redundancy, there is differentiation across the PBP family. Seemingly redundant proteins can be important for enabling an organism to cope with environmental stressors. We sought to evaluate the consequence of environmental pH on PBP enzymatic activity in
Identifiants
pubmed: 36993441
doi: 10.1101/2023.03.20.533529
pmc: PMC10055284
pii:
doi:
Types de publication
Preprint
Langues
eng
Déclaration de conflit d'intérêts
Conflicts of Interest The authors declare that they have no conflicts of interest with the contents of this article.