Prevalence of pulmonary artery dilation in non-cystic fibrosis bronchiectasis: A CT analysis from a cohort of the US Bronchiectasis and Nontuberculous Mycobacteria Research Registry.

Bronchial Diseases hypoxemia nontuberculous mycobacteria pulmonary artery

Journal

Research square
Titre abrégé: Res Sq
Pays: United States
ID NLM: 101768035

Informations de publication

Date de publication:
22 Mar 2023
Historique:
pubmed: 31 3 2023
medline: 31 3 2023
entrez: 30 3 2023
Statut: epublish

Résumé

Although pulmonary artery (PA) dilation is independently associated with significant morbidity and mortality in patients with pulmonary diseases irrespective of diagnosed pulmonary hypertension, its relationship to nontuberculous mycobacteria (NTM) is unknown. To determine the prevalence of PA dilation in patients with NTM-predominant non-CF bronchiectasis, we evaluated the chest computed tomography (CT) scans from 321 patient in the United States based Bronchiectasis and NTM Research Registry. The majority of our cohort had NTM infection. We measured the severity of bronchiectasis using modified Reiff criteria and measured the diameters of the PA and aorta (Ao), with PA dilation defined as a PA:Ao ratio > 0.9. Forty-two patients (13%) were found to have PA dilation. PA dilation was positively associated with the use of supplemental oxygen (

Identifiants

pubmed: 36993456
doi: 10.21203/rs.3.rs-2711488/v1
pmc: PMC10055630
pii:
doi:

Types de publication

Preprint

Langues

eng

Déclaration de conflit d'intérêts

Competing Interests The authors have no relevant financial or non-financial interests to disclose.

Auteurs

Elham Karamooz (E)

Oregon Health & Science University Pulmonary & Critical Care.

Anupama G Brixey (AG)

Cardiothoracic Imaging Section, Department of Diagnostic Radiology, Oregon Health & Science University.

Chara E Rydzak (CE)

Cardiothoracic Imaging Section, Department of Diagnostic Radiology, Oregon Health & Science University.

Steven L Primack (SL)

Cardiothoracic Imaging Section, Department of Diagnostic Radiology, Oregon Health & Science University.

Sheila Markwardt (S)

Oregon Health & Science University-Portland State University School of Public Health.

Alan F Barker (AF)

Oregon Health & Science University Pulmonary & Critical Care.

Classifications MeSH