A Genetic Locus Mediating Attentional Processing.

Attention is required for most higher-order cognitive functions, but despite extensive and careful study, central unifying principles have been challenging to elicit. To provide a new perspective, we took a forward genetics approach to identify genes with large contributions to attentional performance. We studied 200 genetically diverse mice on measures of pre-attentive processing and through genetic mapping identified a small locus on chromosome 13 (95%CI: 92.22- 94.09 Mb), driving substantial variation (19%) in this trait. Further characterization of the locus revealed a causative gene,

Déclaration de conflit d'intérêts

Declaration of Interests: The authors declare no competing interests.