Lymph node metastasis from olfactory neuroblastoma at presentation and as disease relapse: A systematic review and proportion meta-analysis of prevalence data and variables influencing regional control.
elective radiotherapy
esthesioneuroblastoma
neck dissection
nodal metastasis
olfactory neuroblastoma
Journal
Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541
Informations de publication
Date de publication:
06 2023
06 2023
Historique:
revised:
13
02
2023
received:
11
12
2022
accepted:
21
03
2023
medline:
12
5
2023
pubmed:
31
3
2023
entrez:
30
3
2023
Statut:
ppublish
Résumé
Aim of this study is to investigate the prevalence of cervical nodal metastasis at presentation and as disease relapse in primary, treatment-naive olfactory neuroblastoma (ONB), and to review treatment modalities, risk factors for regional failure and survival outcomes according to nodal status. A systematic review and proportion meta-analysis were conducted following PRISMA guidelines based on PubMed, Web of Science, and Scopus. Eighteen articles were examined. The pooled proportion of patients with nodal metastasis at presentation (11.5%) was comparable to that of cN0 patients not receiving elective neck treatment developing nodal metastasis during follow-up (12.3%). Of the latter, most were Kadish stage C tumors (85.5%). Cervical involvement is common both at presentation and during follow-up of cN0 ONB. The highest risk of developing late nodal metastasis is seen in cN0 patients with Kadish stage C tumors not receiving elective neck treatment. Elective cN0 neck treatment should be encouraged in selected patients to increase regional control.
Sections du résumé
BACKGROUND
Aim of this study is to investigate the prevalence of cervical nodal metastasis at presentation and as disease relapse in primary, treatment-naive olfactory neuroblastoma (ONB), and to review treatment modalities, risk factors for regional failure and survival outcomes according to nodal status.
METHODS
A systematic review and proportion meta-analysis were conducted following PRISMA guidelines based on PubMed, Web of Science, and Scopus.
RESULTS
Eighteen articles were examined. The pooled proportion of patients with nodal metastasis at presentation (11.5%) was comparable to that of cN0 patients not receiving elective neck treatment developing nodal metastasis during follow-up (12.3%). Of the latter, most were Kadish stage C tumors (85.5%).
CONCLUSIONS
Cervical involvement is common both at presentation and during follow-up of cN0 ONB. The highest risk of developing late nodal metastasis is seen in cN0 patients with Kadish stage C tumors not receiving elective neck treatment. Elective cN0 neck treatment should be encouraged in selected patients to increase regional control.
Types de publication
Systematic Review
Meta-Analysis
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1486-1496Informations de copyright
© 2023 Wiley Periodicals LLC.
Références
Rinaldo A, Ferlito A, Shaha AR, Wei WI, Lund VJ. Esthesioneuroblastoma and cervical lymph node metastases: clinical and therapeutic implications. Acta Otolaryngol. 2002;122(2):215-221.
Rimmer J, Lund VJ, Beale T, Wei WI, Howard D. Olfactory neuroblastoma: a 35-year experience and suggested follow-up protocol: olfactory neuroblastoma. Laryngoscope. 2014;124(7):1542-1549.
Ow TJ, Bell D, Kupferman ME, DeMonte F, Hanna EY. Esthesioneuroblastoma. Neurosurg Clin N Am. 2013;24(1):51-65.
Abdelmeguid AS, Bell D, Roberts D, et al. Long-term outcomes of olfactory neuroblastoma: MD Anderson Cancer Center experience and review of the literature. Laryngoscope. 2022;132(2):290-297.
Naples JG, Spiro J, Tessema B, Kuwada C, Kuo CL, Brown SM. Neck recurrence and mortality in esthesioneuroblastoma: implications for management of the N0 neck: neck recurrence and mortality in ENB. Laryngoscope. 2016;126(6):1373-1379.
Zanation AM, Ferlito A, Rinaldo A, et al. When, how and why to treat the neck in patients with esthesioneuroblastoma: a review. Eur Arch Otorhinolaryngol. 2010;267(11):1667-1671.
Demiroz C, Gutfeld O, Aboziada M, Brown D, Marentette LJ, Eisbruch A. Esthesioneuroblastoma: is there a need for elective neck treatment? Int J Radiat Oncol. 2011;81(4):e255-e261.
Nalavenkata SB, Sacks R, Adappa ND, et al. Olfactory neuroblastoma: fate of the neck-a long-term multicenter retrospective study. Otolaryngol Neck Surg. 2016;154(2):383-389.
Koka VN, Julieron M, Bourhis J, et al. Aesthesioneuroblastoma. J Laryngol Otol. 1998;112(7):628-633.
Dulguerov P, Allal AS, Calcaterra TC. Esthesioneuroblastoma: a meta-analysis and review. Lancet Oncol. 2001;2(11):683-690.
Peacock J, Harmsen W, Link M, et al. Risk of delayed lymph node metastasis in clinically N0 esthesioneuroblastoma. J Neurol Surg B Skull Base. 2016;78(1):68-74.
Monroe AT, Hinerman RW, Amdur RJ, Morris CG, Mendenhall WM. Radiation therapy for esthesioneuroblastoma: rationale for elective neck irradiation. Head Neck. 2003;25(7):529-534.
Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ. 2009;339:b2700.
https://www.ohri.ca/programs/clinical_epidemiology/oxford.asp.
Freeman MF, Tukey JW. Transformation related to the angular and square root. Ann Math Stat. 1950;21:601-611.
DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7(3):177-188.
Higgins JPT, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21(11):1539-1558.
Higgins JPT. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557-560.
Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629-634.
Loy AH, Reibel JF, Read PW, et al. Esthesioneuroblastoma: continued follow-up of a single institution's experience. Arch Otolaryngol Neck Surg. 2006;132(2):134-138.
Ozsahin M, Gruber G, Olszyk O, et al. Outcome and prognostic factors in olfactory neuroblastoma: a rare cancer network study. Int J Radiat Oncol. 2010;78(4):992-997.
Song CM, Won TB, Lee CH, Kim DY, Rhee CS. Treatment modalities and outcomes of olfactory neuroblastoma. Laryngoscope. 2012;122(11):2389-2395.
Yin Z, Luo J, Gao L, et al. Spread patterns of lymph nodes and the value of elective neck irradiation for esthesioneuroblastoma. Radiother Oncol. 2015;117(2):328-332.
Petruzzelli GJ, Howell JB, Pederson A, et al. Multidisciplinary treatment of olfactory neuroblastoma: patterns of failure and management of recurrence. Am J Otolaryngol. 2015;36(4):547-553.
Jiang W, Mohamed ASR, Fuller CD, et al. The role of elective nodal irradiation for esthesioneuroblastoma patients with clinically negative neck. Pract Radiat Oncol. 2016;6(4):241-247.
Xiong L, Zeng XL, Guo CK, Liu AW, Huang L. Optimal treatment and prognostic factors for esthesioneuroblastoma: retrospective analysis of 187 Chinese patients. BMC Cancer. 2017;17(1):254.
Hwang CS, Seo YW, Park SC, et al. Role of surgical treatment for esthesioneuroblastomas: 31-year experience at a single institution. J Craniomaxillofac Surg. 2017;45(1):120-126.
de Gabory L, Verillaud B, Rumeau C, et al. Multicenter assessment of exclusive endoscopic endonasal approach for the treatment of 53 olfactory neuroblastomas. Head Neck. 2018;40(5):1000-1007.
Yuan Y, Ye J, Qiu H, et al. Exploration of the optimal treatment regimes for esthesioneuroblastoma: a single center experience in China. J Cancer. 2018;9(1):174-181.
Marinelli J, Janus J, Van Gompel J, et al. Dural invasion predicts the laterality and development of neck metastases in esthesioneuroblastoma. J Neurol Surg B Skull Base. 2018;79(5):495-500.
Song X, Huang C, Wang S, Yan L, Wang J, Li Y. Neck management in patients with olfactory neuroblastoma. Oral Oncol. 2020;101:104505.
Ziai H, Yu E, Weinreb I, et al. Regional recurrences and Hyams grade in esthesioneuroblastoma. J Neurol Surg B Skull Base. 2020;82(6):608-614.
Liu T, Sun Q, Qin W, Chen X, Hu Q. Outcome and optimal treatment for esthesioneuroblastoma in the era of intensity-modulated radiation therapy: a single-center experience. Cancer Manag Res. 2020;12:8355-8362.
Wolfe AR, Blakaj D, London N, et al. Clinical outcomes and multidisciplinary patterns of failure for olfactory neuroblastoma: the Ohio state experience. J Neurol Surg B Skull Base. 2020;81(3):287-294.
Zeng Q, Tian Y, He Y, et al. Long-term survival outcomes and treatment experience of 64 patients with esthesioneuroblastoma. Front Oncol. 2021;11:624960.
Davis RE, Weissler MC. Esthesioneuroblastoma and neck metastasis. Head Neck. 1992;14(6):477-482.
De Virgilio A, Costantino A, Sebastiani D, et al. Elective neck irradiation in the management of esthesioneuroblastoma: a systematic review and meta-analysis. Rhinol J. 2021;59(5):433-440.
Marinelli JP, Van Gompel JJ, Link MJ, et al. Volumetric analysis of olfactory neuroblastoma skull base laterality and implications on neck disease: implications of ONB laterality and neck disease. Laryngoscope. 2018;128(4):864-870.
Gore MR, Zanation AM. Salvage treatment of late neck metastasis in esthesioneuroblastoma: a meta-analysis. Arch Otolaryngol Neck Surg. 2009;135(10):1030-1034.