Cerebral oxygenation immediately after birth and long-term outcome in preterm neonates-a retrospective analysis.

BSID III 9 Cerebral regional oxygen saturation (crSO2) 3 Fetal-to-neonatal transition 4 Long-term outcome 8 Morbidity 5 Mortality 6 Near-infrared spectroscopy 2 Neurodevelopmental disability 10 Preterm infant 1 Short-term outcome 7

Journal

BMC pediatrics
ISSN: 1471-2431
Titre abrégé: BMC Pediatr
Pays: England
ID NLM: 100967804

Informations de publication

Date de publication:
30 03 2023
Historique:
received: 14 11 2022
accepted: 20 03 2023
medline: 3 4 2023
entrez: 30 3 2023
pubmed: 31 3 2023
Statut: epublish

Résumé

Prematurity is associated with increased risk for morbidity and mortality. Aim of this study was to evaluate whether cerebral oxygenation during fetal-to-neonatal transition period was associated with long-term outcome in very preterm neonates. Preterm neonates ≤ 32 weeks of gestation and/or ≤ 1500 g with measurements of cerebral regional oxygen saturation (crSO Forty-two preterm neonates were included: adverse outcome group n = 13; favorable outcome group n = 29. Median(IQR) gestational age and birth weight were 24.8 weeks (24.2-29.8) and 760 g (670-1054) in adverse outcome group and 30.6 weeks (28.1-32.0) (p = 0.009*) and 1250 g (972-1390) (p = 0.001*) in the favorable outcome group, respectively. crSO Preterm neonates with adverse outcome had beside lower gestational age also a lower crSO

Sections du résumé

BACKGROUND
Prematurity is associated with increased risk for morbidity and mortality. Aim of this study was to evaluate whether cerebral oxygenation during fetal-to-neonatal transition period was associated with long-term outcome in very preterm neonates.
METHODS
Preterm neonates ≤ 32 weeks of gestation and/or ≤ 1500 g with measurements of cerebral regional oxygen saturation (crSO
RESULTS
Forty-two preterm neonates were included: adverse outcome group n = 13; favorable outcome group n = 29. Median(IQR) gestational age and birth weight were 24.8 weeks (24.2-29.8) and 760 g (670-1054) in adverse outcome group and 30.6 weeks (28.1-32.0) (p = 0.009*) and 1250 g (972-1390) (p = 0.001*) in the favorable outcome group, respectively. crSO
CONCLUSION
Preterm neonates with adverse outcome had beside lower gestational age also a lower crSO

Identifiants

pubmed: 36997902
doi: 10.1186/s12887-023-03960-z
pii: 10.1186/s12887-023-03960-z
pmc: PMC10061688
doi:

Substances chimiques

Oxygen S88TT14065

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

145

Informations de copyright

© 2023. The Author(s).

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Auteurs

Christina H Wolfsberger (CH)

Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Research Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.

Elisabeth Pichler-Stachl (E)

Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.

Nina Höller (N)

Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Research Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.

Lukas P Mileder (LP)

Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Research Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.

Bernhard Schwaberger (B)

Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Research Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.

Alexander Avian (A)

Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.

Berndt Urlesberger (B)

Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Research Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.

Gerhard Pichler (G)

Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria. Gerhard.pichler@medunigraz.at.
Research Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria. Gerhard.pichler@medunigraz.at.

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