Amount and composition of total fatty acids in red and yellow bone marrow are altered with changes in bone mineral density.
Tartrate-Resistant Acidic Phosphatase (TRAP5b)
bone marrow
bone mineral density
fatty acid composition
saturated fatty acids
unsaturated fatty acids
Journal
EXCLI journal
ISSN: 1611-2156
Titre abrégé: EXCLI J
Pays: Germany
ID NLM: 101299402
Informations de publication
Date de publication:
2023
2023
Historique:
received:
17
01
2023
accepted:
07
02
2023
medline:
1
4
2023
entrez:
31
3
2023
pubmed:
1
4
2023
Statut:
epublish
Résumé
There is general consent that with decreasing bone mineral density the amount of marrow adipose tissue increases. While image-based techniques, claim an increase in saturated fatty acids responsible for this effect, this study shows an increase in both saturated and unsaturated fatty acids in the bone marrow. Using fatty acid methyl ester gas chromatography-mass spectrometry, characteristic fatty acid patterns for patients with normal BMD (N = 9), osteopenia (N = 12), and osteoporosis (N = 9) have been identified, which differ between plasma, red bone marrow and yellow bone marrow. Selected fatty acids,
Identifiants
pubmed: 36998704
doi: 10.17179/excli2023-5843
pii: 2023-5843
pmc: PMC10043387
doi:
Types de publication
Journal Article
Langues
eng
Pagination
207-220Informations de copyright
Copyright © 2023 Ehnert et al.
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