Risk factors for blood component therapy in parturients-Case-control study.
anemia
case-control
delivery
hemorrhage
obstetrics
packed cells
Journal
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
ISSN: 1879-3479
Titre abrégé: Int J Gynaecol Obstet
Pays: United States
ID NLM: 0210174
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
revised:
22
02
2023
received:
11
10
2022
accepted:
27
03
2023
medline:
15
8
2023
pubmed:
2
4
2023
entrez:
1
4
2023
Statut:
ppublish
Résumé
Postpartum hemorrhage is a major cause of maternal morbidity and mortality, so early identification of patients at risk is crucial. In this study, we aim to assess the risk factors for major transfusion in parturients. A case-control study was conducted between 2011 and 2019. The cases included women who were treated with postpartum major transfusion compared with two control groups, one of which was treated with 1-2 packed red blood cells and one of which was not treated with packed red blood cells. Cases were matched with controls based on two variables: multiple pregnancies and previous history of three or more cesarean sections. A multivariable conditional logistic regression model was used to determine the role of the independent risk factors. Of the 187 424 deliveries included in the present study, 246 (0.3%) women were treated with major transfusions. After applying a multivariate analysis, maternal age (odds ratio [OR] 1.07, 95% confidence interval [CI] 0.996-1.16), antenatal anemia with hemoglobin less than 10 g/dL (OR 12.58, 95% CI 2.86-55.25), retained placenta (OR 5.5, 95% CI 2.15-13.78), and cesarean delivery (OR 10.12, 95% CI 0.93-1.95) remained independent risk factors for major transfusions. Retained placenta and antenatal anemia (hemoglobin < 10 g/dL) are independent risk factors for major transfusion. Of these, anemia was found to be the most significant.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
906-912Informations de copyright
© 2023 The Authors. International Journal of Gynecology & Obstetrics published by John Wiley & Sons Ltd on behalf of International Federation of Gynecology and Obstetrics.
Références
Picetti R, Miller L, Shakur-Still H, et al. The WOMAN trial: clinical and contextual factors surrounding the deaths of 483 women following post-partum hemorrhage in developing countries. Obstet Gynecol Surv. 2020;75(12):723-725.
Cho GJ, Lee K-M, Kim HY, et al. Postpartum haemorrhage requiring transfusion and risk of cardiovascular disease later in life: a retrospective cohort study. BJOG. 2021;128(4):738-744.
Main EK, McCain CL, Morton CH, Holtby S, Lawton ES. Pregnancy-related mortality in California. Obstet Gynecol. 2015;125(4):938-947.
Committee on Practice Bulletins-Obstetrics. Practice bulletin No. 183: postpartum hemorrhage. Obstet Gynecol. 2017;130(4):e168-e186.
Dahlke JD, Mendez-Figueroa H, Maggio L, et al. Prevention and management of postpartum hemorrhage: a comparison of 4 national guidelines. Am J Obstet Gynecol. 2015;213(1):76.e1-76.e10.
Fuller AJ, Bucklin B. Blood component therapy in obstetrics. Obstet Gynecol Clin North Am. 2007;34(3):443-458.
Sheiner E, Sarid L, Levy A, Seidman DS, Hallak M. Obstetric risk factors and outcome of pregnancies complicated with early postpartum hemorrhage: a population-based study. J Matern Neonatal Med. 2005;18(3):149-154.
Xing Z, He Y, Ji C, et al. Establishing a perinatal red blood cell transfusion risk evaluation model for obstetric patients: a retrospective cohort study. Transfusion. 2019;59(5):1667-1674.
Kawakita T, Mokhtari N, Huang JC, Landy HJ. Evaluation of risk-assessment tools for severe postpartum hemorrhage in women undergoing cesarean delivery. Obstet Gynecol. 2019;134(6):1308-1316.
Silver RM, Landon MB, Rouse DJ, et al. Repeat Cesarean Deliveries. ACOG. 2006;107(6):1226-1232.
Macrosomia: ACOG practice bulletin, number 216. Obstet Gynecol. 2020;135(1):e18-e35.
American College of Obstetricians and Gynecologists (College), Society for Maternal-Fetal Medicine, Caughey AB, Cahill AG, Guise J-M, Rouse DJ. Safe prevention of the primary cesarean delivery. Am J Obstet Gynecol. 2014;210(3):179-193.
Patterson JA, Roberts CL, Bowen JR, et al. Blood transfusion during pregnancy, birth, and the postnatal period. Obstet Gynecol. 2014;123(1):126-133.
Ozumba BC, Ezegwui HU. Blood transfusion and caesarean section in a developing country. J Obstet Gynaecol (Lahore). 2006;26(8):746-748.
Meikle SF, Kuklina EV, Jamieson DJ, et al. Severe obstetric morbidity in the United States: 1998-2005. Obstet Gynecol. 2009;113(2 PART 1):293-299.
Anemia in pregnancy: ACOG practice bulletin summary, number 233. Obstet Gynecol. 2021;138(2):317-319.
Muñoz M, Stensballe J, Ducloy-Bouthors AS, et al. Patient blood management in obstetrics: prevention and treatment of postpartum haemorrhage. A NATA consensus statement: a multidisciplinary consensus statement. Blood Transfus. 2019;17(2):112-136.
Salati JA, Leathersich SJ, Williams MJ, Cuthbert A, Tolosa JE. Prophylactic oxytocin for the third stage of labour to prevent postpartum haemorrhage. Cochrane Database Syst Rev. 2019;4:CD001808.
Reale SC, Easter SR, Xu X, Bateman BT, Farber MK. Trends in postpartum hemorrhage in the United States from 2010 to 2014. Anesth Analg. 2020;130(5):E119-E122.
Sheldon WR, Blum J, Vogel JP, et al. Postpartum haemorrhage management, risks, and maternal outcomes: findings from the World Health Organization multicountry survey on maternal and newborn health. BJOG. 2014;121(Suppl):5-13.
Attali E, Yogev Y. The impact of advanced maternal age on pregnancy outcome. Best Pract Res Clin Obstet Gynaecol. 2021;70:2-9.
Hammad IA, Chauhan SP, Magann EF, Abuhamad AZ. Peripartum complications with cesarean delivery: a review of maternal-fetal medicine units network publications. J Matern Neonatal Med. 2014;27(5):463-474.
da Fonseca EB, Damião R, Moreira DA. Preterm birth prevention. Best Pract Res Clin Obstet Gynaecol. 2020;69:40-49.
Platt MJ. Outcomes in preterm infants. Public Health. 2014;128(5):399-403.
Buhimschi CS, Schatz F, Krikun G, Buhimschi IA, Lockwood CJ. Novel insights into molecular mechanisms of abruption-induced preterm birth. Expert Rev Mol Med. 2010;12:e35.
Al-Farsi YM, Brooks DR, Werler MM, Cabral HJ, Al-Shafei MA, Wallenburg HC. Effect of high parity on occurrence of anemia in pregnancy: a cohort study. BMC Pregnancy Childbirth. 2011;11:7.
D'Alton ME, Rood KM, Smid MC, et al. Intrauterine vacuum-induced hemorrhage-control device for rapid treatment of postpartum hemorrhage. Obstet Gynecol. 2020;136(5):882-891.