Feasibility and usability of a digital health technology system to monitor mobility and assess medication adherence in mild-to-moderate Parkinson's disease.
Parkinson's disease
inertial measurement units
medication adherence
mobility
motor complications
remote monitoring
smartwatch
wearable technology
Journal
Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899
Informations de publication
Date de publication:
2023
2023
Historique:
received:
09
12
2022
accepted:
20
02
2023
medline:
4
4
2023
entrez:
3
4
2023
pubmed:
4
4
2023
Statut:
epublish
Résumé
Parkinson's disease (PD) is a neurodegenerative disorder which requires complex medication regimens to mitigate motor symptoms. The use of digital health technology systems (DHTSs) to collect mobility and medication data provides an opportunity to objectively quantify the effect of medication on motor performance during day-to-day activities. This insight could inform clinical decision-making, personalise care, and aid self-management. This study investigates the feasibility and usability of a multi-component DHTS to remotely assess self-reported medication adherence and monitor mobility in people with Parkinson's (PwP). Thirty participants with PD [Hoehn and Yahr stage I ( Adherence to each device exceeded 70% and ranged from 73 to 97%. Overall, the DHTS was well tolerated with 17/30 participants giving a score > 75% [average score for these participants = 89%, from 0 (worst) to 100 (best)] for its usability. Usability of the DHTS was significantly associated with age (ρ = -0.560, BCa 95% CI [-0.791, -0.207]). This study identified means to improve usability of the DHTS by addressing technical and design issues of the smartwatch. Feasibility, usability and acceptability were identified as key themes from PwP qualitative feedback on the DHTS. This study highlighted the feasibility and usability of our integrated DHTS to remotely assess medication adherence and monitor mobility in people with mild-to-moderate Parkinson's disease. Further work is necessary to determine whether this DHTS can be implemented for clinical decision-making to optimise management of PwP.
Identifiants
pubmed: 37006505
doi: 10.3389/fneur.2023.1111260
pmc: PMC10050691
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1111260Informations de copyright
Copyright © 2023 Debelle, Packer, Beales, Bailey, Mc Ardle, Brown, Hunter, Ciravegna, Ireson, Evers, Niessen, Shi, Yarnall, Rochester, Alcock and Del Din.
Déclaration de conflit d'intérêts
FC was CEO and shareholder of Aeqora Ltd. McRoberts is the manufacturer of the DynaPort. MN and JE are employees of McRoberts. SDD reports consultancy activity with Hoffmann-La Roche Ltd outside of this study. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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