The impact of preoperative nutritional screening, ERAS protocol, and mini-invasive surgery in surgical oncology: A multi-institutional SEM analysis of patients with digestive cancer.

digestive cancers mini-invasive surgery nutritional screening structural equation modeling (SEM) surgical oncology

Journal

Frontiers in nutrition
ISSN: 2296-861X
Titre abrégé: Front Nutr
Pays: Switzerland
ID NLM: 101642264

Informations de publication

Date de publication:
2023
Historique:
received: 10 09 2022
accepted: 20 02 2023
medline: 4 4 2023
entrez: 3 4 2023
pubmed: 4 4 2023
Statut: epublish

Résumé

Mini-invasive surgery (MIS), ERAS, and preoperative nutritional screening are currently used to reduce complications and the length of hospital stay (LOS); however, inter-variable correlations have seldom been explored. This research aimed to define inter-variable correlations in a large series of patients with gastrointestinal cancer and their impact on outcomes. Patients with consecutive cancer who underwent radical gastrointestinal surgery between 2019 and 2020 were analyzed. Age, BMI, comorbidities, ERAS, nutritional screening, and MIS were evaluated to determine their impact on 30-day complications and LOS. Inter-variable correlations were measured, and a latent variable was computed to define the patients' Of the 1,968 eligible patients, 1,648 were analyzed. Univariable analyses documented the benefit of nutritional screening for LOS and MIS and ERAS (≥7 items) for LOS and complications; conversely, being male and comorbidities correlated with complications, while increased age and BMI correlated with worse outcomes. SEM analysis revealed that (a) the latent variable is explained by the use of nutritional screening (p0·004); (b) the variables were correlated (age-comorbidity, ERAS-MIS, and ERAS-nutritional screening, Enhanced recovery after surgery (ERAS), MIS, and nutritional screening are beneficial in surgical oncology; however, the inter-variable correlation is reliable, underlying the importance of the multidisciplinary approach.

Sections du résumé

Background UNASSIGNED
Mini-invasive surgery (MIS), ERAS, and preoperative nutritional screening are currently used to reduce complications and the length of hospital stay (LOS); however, inter-variable correlations have seldom been explored. This research aimed to define inter-variable correlations in a large series of patients with gastrointestinal cancer and their impact on outcomes.
Methods UNASSIGNED
Patients with consecutive cancer who underwent radical gastrointestinal surgery between 2019 and 2020 were analyzed. Age, BMI, comorbidities, ERAS, nutritional screening, and MIS were evaluated to determine their impact on 30-day complications and LOS. Inter-variable correlations were measured, and a latent variable was computed to define the patients'
Results UNASSIGNED
Of the 1,968 eligible patients, 1,648 were analyzed. Univariable analyses documented the benefit of nutritional screening for LOS and MIS and ERAS (≥7 items) for LOS and complications; conversely, being male and comorbidities correlated with complications, while increased age and BMI correlated with worse outcomes. SEM analysis revealed that (a) the latent variable is explained by the use of nutritional screening (p0·004); (b) the variables were correlated (age-comorbidity, ERAS-MIS, and ERAS-nutritional screening,
Conclusion UNASSIGNED
Enhanced recovery after surgery (ERAS), MIS, and nutritional screening are beneficial in surgical oncology; however, the inter-variable correlation is reliable, underlying the importance of the multidisciplinary approach.

Identifiants

pubmed: 37006925
doi: 10.3389/fnut.2023.1041153
pmc: PMC10063158
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1041153

Informations de copyright

Copyright © 2023 Lorenzon, Caccialanza, Casalone, Santoro, Delrio, Izzo, Tonello, Mele, Pozzo, Pedrazzoli, Pietrabissa, Fenu, Mellano, Fenocchio, Avallone, Bergamo, Nardi, Persiani, Biondi, Tirelli, Agnes, Ferraris, Quarà, Milanesio, Ribero, Rinaldi, D'Elia, Rho, Cenzi and D'Ugo.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Eur J Surg Oncol. 2018 Apr;44(4):509-514
pubmed: 29398322
Aging Clin Exp Res. 2018 Mar;30(3):249-252
pubmed: 29453605
Updates Surg. 2020 Jun;72(2):355-378
pubmed: 32306277
Br J Surg. 2010 Jan;97(1):92-7
pubmed: 20013933
Medicine (Baltimore). 2020 Jan;99(1):e18667
pubmed: 31895832
Lancet. 2007 Oct 20;370(9596):1453-7
pubmed: 18064739
Support Care Cancer. 2009 Mar;17(3):279-84
pubmed: 18581148
Ann Transl Med. 2017 Mar;5(5):102
pubmed: 28361067
Langenbecks Arch Surg. 2022 Jun;407(4):1637-1646
pubmed: 35275247
Behav Res Methods. 2019 Feb;51(1):409-428
pubmed: 29869222
Int J Gynecol Cancer. 2019 Mar 20;:
pubmed: 30898937
Ann Surg Oncol. 2019 Aug;26(8):2622-2630
pubmed: 31123932
Nutrition. 2018 Jun;50:74-81
pubmed: 29547797
Ann Surg. 2018 Jan;267(1):57-65
pubmed: 28437313
Clin Nutr ESPEN. 2018 Jun;25:139-144
pubmed: 29779809
J Clin Epidemiol. 2006 Aug;59(8):836-41
pubmed: 16828677
Eur J Surg Oncol. 2018 Apr;44(4):469-483
pubmed: 29422252
JPEN J Parenter Enteral Nutr. 2014 Feb;38(2):196-204
pubmed: 24748626
Ann Surg Oncol. 2020 Jun;27(6):2025-2032
pubmed: 31848820
J Chronic Dis. 1987;40(5):373-83
pubmed: 3558716
J Am Coll Surg. 2020 Apr;230(4):451-460
pubmed: 32113029
J Geriatr Oncol. 2018 Jan;9(1):74-80
pubmed: 28888553
Clin Nutr ESPEN. 2020 Jun;37:141-147
pubmed: 32359736
Educ Psychol Meas. 2020 Jun;80(3):421-445
pubmed: 32425213
BMC Res Notes. 2010 Oct 22;3:267
pubmed: 20969789
Int J Epidemiol. 2009 Apr;38(2):549-51
pubmed: 19153137
Clin Nutr ESPEN. 2022 Feb;47:391-398
pubmed: 35063232
World J Surg. 2019 Oct;43(10):2490-2498
pubmed: 31240434
Acta Psychiatr Scand. 2006 Apr;113(4):322-31
pubmed: 16638077
Eur J Surg Oncol. 2020 Nov;46(11):2074-2082
pubmed: 32938568
Updates Surg. 2022 Dec;74(6):1839-1849
pubmed: 36279038
Nutr Cancer. 2018 Nov-Dec;70(8):1254-1263
pubmed: 30686045
Lancet. 1995 Mar 25;345(8952):763-4
pubmed: 7891489

Auteurs

Laura Lorenzon (L)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.

Riccardo Caccialanza (R)

Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Valentina Casalone (V)

Candiolo Cancer Institute-IRCCS, Turin, Italy.

Gloria Santoro (G)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.

Paolo Delrio (P)

Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione Giovanni Pascale IRCCS, Naples, Italy.

Francesco Izzo (F)

Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione Giovanni Pascale IRCCS, Naples, Italy.

Marco Tonello (M)

Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.

Maria Cristina Mele (MC)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.

Carmelo Pozzo (C)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.

Paolo Pedrazzoli (P)

Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Andrea Pietrabissa (A)

Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Piero Fenu (P)

Candiolo Cancer Institute-IRCCS, Turin, Italy.

Alfredo Mellano (A)

Candiolo Cancer Institute-IRCCS, Turin, Italy.

Elisabetta Fenocchio (E)

Candiolo Cancer Institute-IRCCS, Turin, Italy.

Antonio Avallone (A)

Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione Giovanni Pascale IRCCS, Naples, Italy.

Francesca Bergamo (F)

Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.

Maria Teresa Nardi (MT)

Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.

Roberto Persiani (R)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.

Alberto Biondi (A)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.

Flavio Tirelli (F)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.

Annamaria Agnes (A)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.

Renato Ferraris (R)

Candiolo Cancer Institute-IRCCS, Turin, Italy.

Virginia Quarà (V)

Candiolo Cancer Institute-IRCCS, Turin, Italy.

Michela Milanesio (M)

Candiolo Cancer Institute-IRCCS, Turin, Italy.

Dario Ribero (D)

Candiolo Cancer Institute-IRCCS, Turin, Italy.

Marilena Rinaldi (M)

Candiolo Cancer Institute-IRCCS, Turin, Italy.

Paola D'Elia (P)

Candiolo Cancer Institute-IRCCS, Turin, Italy.

Maurizio Rho (M)

Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione Giovanni Pascale IRCCS, Naples, Italy.

Carola Cenzi (C)

Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.

Domenico D'Ugo (D)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.

Classifications MeSH