Colorectal adenocarcinoma presenting with a pathological fracture due to a solitary bone metastasis to the tibia: a case report and literature review.

colorectal cancer osseous metastasis pathological fracture

Journal

Przeglad gastroenterologiczny
ISSN: 1895-5770
Titre abrégé: Prz Gastroenterol
Pays: Poland
ID NLM: 101280380

Informations de publication

Date de publication:
2023
Historique:
received: 29 10 2021
accepted: 12 12 2021
medline: 4 4 2023
entrez: 3 4 2023
pubmed: 4 4 2023
Statut: ppublish

Résumé

Solitary bone metastasis of colorectal carcinoma (CRC) without other metastasis sites is extremely rare and can be found in less than 1% of patients with CRC. In the present study, we report the first case of a solitary tibia metastasis and its pathologic fracture as the first presenting feature of a colorectal adenocarcinoma. A 78-year-old female patient presented to our emergency department due to atraumatic pretibial swelling. Plain radiography did not detect any pathology. The swelling was incised and serous-bloody collection was evacuated, and the patient was discharged. On the 17 Solitary bone metastases are most commonly found in bones that are related to venous drainage via the paravertebral plexus of Batson - the pelvis, vertebrae, and sacrum. Long bones are extremely rare localizations of solitary CRC metastases, with only few cases published so far in medical literature. In our case, the patient`s first symptom was related to the osseous tibial metastasis - leg swelling. No tumour was suspected until the pathologic fracture occurred. It is important to consider osseous metastasis in every patient with unexplained swelling, haematoma, or pain of the extremities and make a bone scan to recognize the metastasis early.

Identifiants

pubmed: 37007751
doi: 10.5114/pg.2023.126044
pii: 50389
pmc: PMC10050980
doi:

Types de publication

Journal Article

Langues

eng

Pagination

115-122

Informations de copyright

Copyright © 2023 Termedia.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Branko Bakula (B)

Department of Surgery, University Hospital Sveti Duh, Zagreb, Croatia.

Andrija Karačić (A)

Department of Surgery, University Hospital Sveti Duh, Zagreb, Croatia.

Gabrijela Stanić (G)

Department of Pathology, University Hospital Sveti Duh, Zagreb, Croatia.

Ivan Romić (I)

Department of Surgery, University Hospital Centre Zagreb, Zagreb, Croatia.

Mirko Bakula (M)

Department of Urology, University Hospital Centre Zagreb, Zagreb, Croatia.

Ante Bogut (A)

Department of Gastroenterology, University Hospital Mostar, Mostar, Bosnia and Herzegovinia.

Classifications MeSH