Exploration of genotype-by-environment interactions affecting gene expression responses in porcine immune cells.
G×E
PBMC
allele-specific expression (ASE)
cis-regulatory variation
eQTL
genotype-by-environment interaction
pig
Journal
Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621
Informations de publication
Date de publication:
2023
2023
Historique:
received:
02
02
2023
accepted:
06
03
2023
medline:
4
4
2023
entrez:
3
4
2023
pubmed:
4
4
2023
Statut:
epublish
Résumé
As one of the keys to healthy performance, robustness of farm animals is gaining importance, and with this comes increasing interest in genetic dissection of genotype-by-environment interactions (G×E). Changes in gene expression are among the most sensitive responses conveying adaptation to environmental stimuli. Environmentally responsive regulatory variation thus likely plays a central role in G×E. In the present study, we set out to detect action of environmentally responsive
Identifiants
pubmed: 37007953
doi: 10.3389/fgene.2023.1157267
pii: 1157267
pmc: PMC10061014
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1157267Informations de copyright
Copyright © 2023 Murani and Hadlich.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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