Difficulties in Differentiating Osteosclerosis in Patients With Multifocal Micronodular Pneumocyte Hyperplasia and Cancer.
cisplatin
mtor
multifocal micronodular pneumocyte hyperplasia
multiple sclerotic bone lesions
tuberous sclerosis complex
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Mar 2023
Mar 2023
Historique:
accepted:
28
02
2023
medline:
4
4
2023
entrez:
3
4
2023
pubmed:
4
4
2023
Statut:
epublish
Résumé
A 52-year-old woman with multifocal micronodular pneumocyte hyperplasia in bilateral lungs and multiple sclerotic bone lesions (SBLs) visited our hospital. Tuberous sclerosis complex (TSC) was suspected but did not meet the diagnostic criteria. Ten years later, at age 62, the patient developed ureteral cancer. Cisplatin-containing chemotherapy ameliorated ureteral tumor, concomitant with exacerbation of SBLs. It was difficult to distinguish whether the exacerbation of SBLs was due to exacerbation of TSC or bone metastasis of cancer. The administration of cisplatin made the diagnosis even more difficult because its molecular biological effects can exacerbate the complications of TSC.
Identifiants
pubmed: 37009387
doi: 10.7759/cureus.35659
pmc: PMC10065850
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e35659Informations de copyright
Copyright © 2023, Kumamoto et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Biosci Rep. 2019 Mar 19;39(3):
pubmed: 30842342
Clin Nucl Med. 2001 Jan;26(1):50-2
pubmed: 11139053
Pediatr Radiol. 2016 May;46(5):689-94
pubmed: 26965910
Australas Radiol. 1996 Feb;40(1):77-9
pubmed: 8838896
Clin Imaging. 2013 Mar-Apr;37(2):382-5
pubmed: 23465998
Pathol Int. 2001 Aug;51(8):585-94
pubmed: 11564212
PLoS Genet. 2015 Aug 04;11(8):e1005426
pubmed: 26241748
Ann N Y Acad Sci. 1991;615:125-7
pubmed: 2039137
J Bone Miner Res. 2015 Jul;30(7):1195-205
pubmed: 25639352
Pediatr Neurol. 2013 Oct;49(4):243-54
pubmed: 24053982
BMC Pulm Med. 2022 Mar 5;22(1):77
pubmed: 35248007
Radiology. 2010 Mar;254(3):851-7
pubmed: 20177097
Biochem Biophys Res Commun. 2010 Apr 9;394(3):600-5
pubmed: 20214883
Mol Cell Biol. 2017 Mar 17;37(7):
pubmed: 28069737
J Med Genet. 1989 Jan;26(1):28-31
pubmed: 2918523