Tau-mediated axonal degeneration is prevented by activation of the Wld
Wallerian degeneration
WldS
axonal degeneration
tauopathy
Journal
Brain communications
ISSN: 2632-1297
Titre abrégé: Brain Commun
Pays: England
ID NLM: 101755125
Informations de publication
Date de publication:
2023
2023
Historique:
received:
23
12
2021
revised:
30
08
2022
accepted:
07
03
2023
medline:
5
4
2023
entrez:
4
4
2023
pubmed:
5
4
2023
Statut:
epublish
Résumé
Tauopathy is characterized by neuronal dysfunction and degeneration occurring as a result of changes to the microtubule-associated protein tau. The neuronal changes evident in tauopathy bear striking morphological resemblance to those reported in models of Wallerian degeneration. The mechanisms underpinning Wallerian degeneration are not fully understood although it can be delayed by the expression of the slow Wallerian degeneration (Wld
Identifiants
pubmed: 37013175
doi: 10.1093/braincomms/fcad052
pii: fcad052
pmc: PMC10066515
doi:
Types de publication
Journal Article
Langues
eng
Pagination
fcad052Informations de copyright
© The Author(s) 2023. Published by Oxford University Press on behalf of the Guarantors of Brain.
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest.
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