An Analysis of Lidocaine Usage in the Treatment of Squamous Cell Carcinoma.
cancer treatment
lidocaine
mohs surgery
squamous cell carcinoma
xylocaine
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Feb 2023
Feb 2023
Historique:
accepted:
29
12
2022
medline:
7
4
2023
entrez:
6
4
2023
pubmed:
7
4
2023
Statut:
epublish
Résumé
Squamous cell carcinoma (SCC) is a form of skin cancer that can be treated using a procedure known as Mohs surgery. Mohs surgery is a safe and effective procedure for eliminating SCC. This surgery requires the usage of an analgesic known as lidocaine. Additional anesthetics were also reported to be necessary for this procedure to be conducted in a manner that significantly minimizes patient harm. According to the review, it was found that SCC was treated with lidocaine as a topical analgesic outside of Mohs surgery. This review analyzes the usage of lidocaine in the treatment of SCC. It was also discovered that lidocaine, as an agent, has the potential to slow the progression of SCC, but more research is needed to see if this is truly the case. On average, it was reported that the concentration of lidocaine used in the in vivo studies was significantly higher than that in the in vitro investigations. Further exploration may be needed to verify the conclusions that were based on the analysis of the papers within the review.
Identifiants
pubmed: 37021063
doi: 10.7759/cureus.35614
pmc: PMC10069794
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e35614Informations de copyright
Copyright © 2023, Maalouf et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Ann Palliat Med. 2017 Apr;6(2):165-172
pubmed: 28061538
Am J Otolaryngol. 1995 Jan-Feb;16(1):49-52
pubmed: 7717473
Photodiagnosis Photodyn Ther. 2016 Jun;14:170-2
pubmed: 27102062
Semin Plast Surg. 2008 Nov;22(4):247-56
pubmed: 20567701
Anticancer Res. 2012 Jul;32(7):2925-33
pubmed: 22753757
Cancer. 1998 Jul 1;83(1):148-57
pubmed: 9655305
J Am Acad Dermatol. 2009 Oct;61(4):639-43
pubmed: 19751881
Clin Dermatol. 2019 Jul - Aug;37(4):373-378
pubmed: 31345326
J Pharm Pharmacol. 2018 Jul;70(7):874-882
pubmed: 29633269
J Pain Symptom Manage. 2011 Jul;42(1):126-33
pubmed: 21306862
Adv Drug Deliv Rev. 2020 Jan 1;153:87-108
pubmed: 32497707
Int J Clin Oncol. 2014;19(3):557-562
pubmed: 23797211
Am J Cancer Res. 2011 Jan 1;1(3):275-300
pubmed: 21938273
Arch Dermatol. 1995 Feb;131(2):164-9
pubmed: 7857112
Can J Anaesth. 2004 Oct;51(8):838-41
pubmed: 15470176
J Craniomaxillofac Surg. 2015 Oct;43(8):1567-70
pubmed: 26210304
Anesthesiology. 1995 Feb;82(2):593-6
pubmed: 7856922
World J Clin Oncol. 2015 Feb 10;6(1):7-15
pubmed: 25667910
J Pain Palliat Care Pharmacother. 2018 Mar;32(1):15-19
pubmed: 29737933
J Palliat Med. 2019 Mar;22(3):343-347
pubmed: 30508406
J Clin Oncol. 2023 Feb 20;41(6):1228-1238
pubmed: 36441987
Bioengineered. 2022 Mar;13(3):6359-6370
pubmed: 35212616
J Craniomaxillofac Surg. 1993 Jun;21(4):157-62
pubmed: 8335727
Nucl Med Commun. 2008 Apr;29(4):318-22
pubmed: 18317294
Plast Reconstr Surg. 2004 Nov;114(6):82e-94e
pubmed: 15509920
Ann Thorac Med. 2012 Jan;7(1):21-5
pubmed: 22347346
J Pain Symptom Manage. 1995 May;10(4):310-4
pubmed: 7541437
J Pain Palliat Care Pharmacother. 2015;29(4):359-64
pubmed: 26654408
Mayo Clin Proc. 1993 Oct;68(10):1016-20
pubmed: 8412352
Arch Plast Surg. 2013 May;40(3):251-5
pubmed: 23730603