ACR TI-RADS Score combined with cytopathology classification improves the risk stratification of indeterminate thyroid nodules.
Journal
Minerva endocrinology
ISSN: 2724-6116
Titre abrégé: Minerva Endocrinol (Torino)
Pays: Italy
ID NLM: 101777342
Informations de publication
Date de publication:
06 Apr 2023
06 Apr 2023
Historique:
entrez:
6
4
2023
pubmed:
7
4
2023
medline:
7
4
2023
Statut:
aheadofprint
Résumé
The aim of this retrospective study was the elaboration of a new diagnostic model that integrate cytological reports (2017 Bethesda System for Reporting Thyroid Cytopathology) with ultrasonographic features (based on ACR TI-RADS score) to achieve a more accurate definition of indeterminate thyroid nodule malignancy risk. Ninety patients submitted to thyroidectomy were divided in three classes: low malignancy risk (AUS/FLUS with TI-RADS 2/TI-RADS 3 and FN/SFN with TI-RADS 2), intermediate malignancy risk (AUS/FLUS with TI-RADS 4/TI-RADS 5 and FN/SFN with TI-RADS 3/TI-RADS 4), and high malignancy risk (FN/SFN with TI-RADS 5). The surgical approach should be recommended in high-risk patients (81.82% of malignancies), carefully evaluated in intermediate risk (25.42%), whereas a conservative approach can be adopted in low-risk patients (0.00%). The integration of these two multiparametric systems in a Cyto-US score has proven to be a feasible and reliable aid to achieve a more accurate definition of malignancy risk.
Sections du résumé
BACKGROUND
BACKGROUND
The aim of this retrospective study was the elaboration of a new diagnostic model that integrate cytological reports (2017 Bethesda System for Reporting Thyroid Cytopathology) with ultrasonographic features (based on ACR TI-RADS score) to achieve a more accurate definition of indeterminate thyroid nodule malignancy risk.
METHODS
METHODS
Ninety patients submitted to thyroidectomy were divided in three classes: low malignancy risk (AUS/FLUS with TI-RADS 2/TI-RADS 3 and FN/SFN with TI-RADS 2), intermediate malignancy risk (AUS/FLUS with TI-RADS 4/TI-RADS 5 and FN/SFN with TI-RADS 3/TI-RADS 4), and high malignancy risk (FN/SFN with TI-RADS 5).
RESULTS
RESULTS
The surgical approach should be recommended in high-risk patients (81.82% of malignancies), carefully evaluated in intermediate risk (25.42%), whereas a conservative approach can be adopted in low-risk patients (0.00%).
CONCLUSIONS
CONCLUSIONS
The integration of these two multiparametric systems in a Cyto-US score has proven to be a feasible and reliable aid to achieve a more accurate definition of malignancy risk.
Identifiants
pubmed: 37021922
pii: S2724-6507.22.03929-X
doi: 10.23736/S2724-6507.22.03929-X
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM