Ten-year Experience of Surgical Management of Paget-Schroetter Syndrome.


Journal

Annals of vascular surgery
ISSN: 1615-5947
Titre abrégé: Ann Vasc Surg
Pays: Netherlands
ID NLM: 8703941

Informations de publication

Date de publication:
Oct 2023
Historique:
received: 14 04 2022
revised: 03 03 2023
accepted: 12 03 2023
medline: 25 9 2023
pubmed: 7 4 2023
entrez: 6 4 2023
Statut: ppublish

Résumé

Paget-Schroetter syndrome (PSS) or effort-induced thrombosis is an acute (<14 days) venous thrombosis of the axillosubclavian vein. Early catheter-directed thrombolysis (CDT) is required to improve patency rate and avoid postthrombotic syndrome. This study aimed to report the management of PSS in our center across 10 years and compare it to the established guidelines. Some of the selected patients were treated with CDT if the diagnosis of acute vein thrombosis was established 6 weeks after the appearance of the first symptoms and if a vascular surgeon was involved in the care and management of the patient. Patients underwent first rib removal 6 weeks after the CDT. Some patients with primary upper limb venous thrombosis were not immediately referred to a vascular surgeon after the initial diagnosis. They were instead discharged home with the prescription of oral anticoagulation therapy (OAT) alone for at least 3 months. Between 2010 and 2020, 426 first rib removal procedures were performed for 338 patients with thoracic outlet syndrome (TOS) at our center. Among them, 18 (4.2%) patients with PSS were identified. 5 (27.8%) patients underwent CDT. The median duration between first symptoms and thrombolysis was 10 days (range, 1-32). Thirteen (72.2%) patients were discharged home with OAT alone and referred to a vascular surgeon with a median time of 365 days (range, 8-6,422) for TOS diagnosis. Postthrombotic syndrome was noticed in 5 (38%) patients in the OAT group and 1 (20%) patient in the CDT group. Despite the guidelines being in favor of early CDT in PSS, most patients are discharged home with OAT alone. The study findings demonstrate that better information about this specific complication must be provided to the concerned practitioners who are likely to encounter such patients.

Sections du résumé

BACKGROUND BACKGROUND
Paget-Schroetter syndrome (PSS) or effort-induced thrombosis is an acute (<14 days) venous thrombosis of the axillosubclavian vein. Early catheter-directed thrombolysis (CDT) is required to improve patency rate and avoid postthrombotic syndrome. This study aimed to report the management of PSS in our center across 10 years and compare it to the established guidelines.
METHODS METHODS
Some of the selected patients were treated with CDT if the diagnosis of acute vein thrombosis was established 6 weeks after the appearance of the first symptoms and if a vascular surgeon was involved in the care and management of the patient. Patients underwent first rib removal 6 weeks after the CDT. Some patients with primary upper limb venous thrombosis were not immediately referred to a vascular surgeon after the initial diagnosis. They were instead discharged home with the prescription of oral anticoagulation therapy (OAT) alone for at least 3 months.
RESULTS RESULTS
Between 2010 and 2020, 426 first rib removal procedures were performed for 338 patients with thoracic outlet syndrome (TOS) at our center. Among them, 18 (4.2%) patients with PSS were identified. 5 (27.8%) patients underwent CDT. The median duration between first symptoms and thrombolysis was 10 days (range, 1-32). Thirteen (72.2%) patients were discharged home with OAT alone and referred to a vascular surgeon with a median time of 365 days (range, 8-6,422) for TOS diagnosis. Postthrombotic syndrome was noticed in 5 (38%) patients in the OAT group and 1 (20%) patient in the CDT group.
CONCLUSIONS CONCLUSIONS
Despite the guidelines being in favor of early CDT in PSS, most patients are discharged home with OAT alone. The study findings demonstrate that better information about this specific complication must be provided to the concerned practitioners who are likely to encounter such patients.

Identifiants

pubmed: 37023925
pii: S0890-5096(23)00181-4
doi: 10.1016/j.avsg.2023.03.014
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

328-334

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Eva Deveze (E)

Vascular and Thoracic Surgery, University Hospital, Angers, France. Electronic address: Eva.Deveze@chu-angers.fr.

Myriam Ammi (M)

Vascular and Thoracic Surgery, University Hospital, Angers, France.

Jeanne Hersant (J)

Vascular Medicine, University Hospital, Angers, France.

Xavier Papon (X)

Vascular and Thoracic Surgery, University Hospital, Angers, France.

Samir Henni (S)

Vascular Medicine, University Hospital, Angers, France.

Pierre Abraham (P)

Vascular Medicine, University Hospital, Angers, France; UMR CNRS6015-INSERM-1083, Mitovasc Institute, University of Angers, Angers, France.

Jean Picquet (J)

Vascular and Thoracic Surgery, University Hospital, Angers, France.

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