Differentiation of silent corticotroph pituitary neuroendocrine tumors (PitNETs) from non-functioning PitNETs using kinetic analysis of dynamic MRI.


Journal

Japanese journal of radiology
ISSN: 1867-108X
Titre abrégé: Jpn J Radiol
Pays: Japan
ID NLM: 101490689

Informations de publication

Date de publication:
Sep 2023
Historique:
received: 19 01 2023
accepted: 25 03 2023
medline: 1 9 2023
pubmed: 8 4 2023
entrez: 7 4 2023
Statut: ppublish

Résumé

Silent corticotroph pituitary adenomas (SCAs)/pituitary neuroendocrine tumors (PitNETs) are common non-functioning pituitary adenomas (NFAs)/PitNETs with a clinically aggressive course. This study aimed to investigate the ability of time-intensity analysis of dynamic magnetic resonance imaging (MRI) for distinguishing adrenocorticotropic hormone (ACTH)-positive SCAs and ACTH-negative SCAs from other NFAs. We retrospectively evaluated the dynamic MRI findings of patients with NFAs. The initial slope of the kinetic curve (slope A total of 106 patients with NFAs (11 ACTH-positive SCAs, 5 ACTH-negative SCAs, and 90 other NFAs) were evaluated. The kinetic curves of ACTH-positive SCAs had significantly lesser slope Dynamic MRI can distinguish ACTH-positive SCAs and ACTH-negative SCAs from other NFAs.

Identifiants

pubmed: 37027094
doi: 10.1007/s11604-023-01420-3
pii: 10.1007/s11604-023-01420-3
pmc: PMC10468932
doi:

Substances chimiques

Adrenocorticotropic Hormone 9002-60-2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

938-946

Informations de copyright

© 2023. The Author(s).

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Auteurs

Taishi Amano (T)

Department of Diagnostic and Interventional Radiology, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan. taishi-amano@umin.ac.jp.

Tomohiko Masumoto (T)

Department of Diagnostic Radiology, Toranomon Hospital, Minato-ku, Tokyo, Japan.

Daisuke Watanabe (D)

Department of Diagnostic and Interventional Radiology, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan.

Sodai Hoshiai (S)

Department of Diagnostic and Interventional Radiology, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan.

Kensaku Mori (K)

Department of Diagnostic and Interventional Radiology, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan.

Noriaki Sakamoto (N)

Department of Diagnostic Pathology, University of Tsukuba Hospital, Tsukuba, Ibaraki, Japan.

Hiroyoshi Kino (H)

Department of Neurosurgery, University of Tsukuba Hospital, Tsukuba, Ibaraki, Japan.

Hiroyoshi Akutsu (H)

Department of Neurosurgery, Dokkyo Medical University, Shimotsuga-gun, Tochigi, Japan.

Takahito Nakajima (T)

Department of Diagnostic and Interventional Radiology, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan.

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