Does longer peripheral intravenous catheter length optimise antimicrobial delivery? Protocol for the LEADER study.

Adult Humans Anti-Infective Agents Health Care Costs Catheterization, Peripheral / adverse effects Catheter-Related Infections / prevention & control Catheters / adverse effects Randomized Controlled Trials as Topic
Randomised controlled trial Study protocol Vascular access

Journal

British journal of nursing (Mark Allen Publishing)
ISSN: 0966-0461
Titre abrégé: Br J Nurs
Pays: England
ID NLM: 9212059

Informations de publication

Date de publication:
06 Apr 2023
Historique:
medline: 11 4 2023
entrez: 7 4 2023
pubmed: 8 4 2023
Statut: ppublish

Résumé

Hospitalised patients receiving intravenous antimicrobial therapy require a reliable device through which this is delivered. Short peripheral intravenous catheters (PIVCs) are the default device for antimicrobial therapy but up to half fail before therapy completion, leading to suboptimal drug dosing, patient distress from repeated insertions, and increased healthcare costs. This study will investigate the use of long PIVCs to determine if they are more reliable at delivering antimicrobial therapy. A two-arm, parallel randomised controlled trial of hospitalised adults requiring at least 3 days of peripherally compatible intravenous antimicrobials. Participants will be randomised to a short (<4 cm) or long (4.5-6.4 cm) PIVC. After interim analysis (

Sections du résumé

BACKGROUND BACKGROUND
Hospitalised patients receiving intravenous antimicrobial therapy require a reliable device through which this is delivered. Short peripheral intravenous catheters (PIVCs) are the default device for antimicrobial therapy but up to half fail before therapy completion, leading to suboptimal drug dosing, patient distress from repeated insertions, and increased healthcare costs. This study will investigate the use of long PIVCs to determine if they are more reliable at delivering antimicrobial therapy.
METHODS METHODS
A two-arm, parallel randomised controlled trial of hospitalised adults requiring at least 3 days of peripherally compatible intravenous antimicrobials. Participants will be randomised to a short (<4 cm) or long (4.5-6.4 cm) PIVC. After interim analysis (

Identifiants

DOI: 10.12968/bjon.2023.32.7.S24 PMID: 37027419
pubmed: 37027419
doi: 10.12968/bjon.2023.32.7.S24
doi:

Substances chimiques

Anti-Infective Agents 0

Types de publication

Clinical Trial Protocol Journal Article

Langues

eng

Pagination

S24-S30

Auteurs

Amanda Corley (A)

Research Fellow (Clinician Researcher), School of Nursing and Midwifery, Griffith University, Nathan, Australia/Nursing and Midwifery Research Centre, Royal Brisbane and Women's Hospital, Herston, Australia.

Catherine O'Brien (C)

Nurse Researcher, Nursing and Midwifery Research Centre, Royal Brisbane and Women's Hospital.

Emily Larsen (E)

Research Fellow (Vascular Access), School of Nursing and Midwifery, Griffith University/Nursing and Midwifery Research Centre, Royal Brisbane and Women's Hospital.

Hannah Peach (H)

Clinical Research Nurse, Nursing and Midwifery Research Centre, Royal Brisbane and Women's Hospital.

Claire Rickard (C)

Professor of Infection Prevention and Vascular Access, School of Nursing, Midwifery and Social Work, The University of Queensland, Brisbane, Australia/Herston Infectious Diseases Institute, Metro North Health, Herston, Australia.

Barbara Hewer (B)

Clinical Nurse Consultant, Vascular Access and Surveillance and Education, Royal Brisbane and Women's Hospital.

India Pearse (I)

Nurse Researcher, Nursing and Midwifery Research Centre, Royal Brisbane and Women's Hospital.

Mary Fenn (M)

Senior Research Assistant, School of Nursing and Midwifery, Griffith University.

Ruth Cocksedge (R)

Senior Research Assistant, School of Medicine and Dentistry, Griffith University.

Nicole Marsh (N)

Nursing and Midwifery Director, Research, Nursing and Midwifery Research Centre, Royal Brisbane and Women's Hospital/Professor, School of Nursing and Midwifery, Griffith University.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Does longer peripheral intravenous catheter...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Does longer peripheral intravenous catheter...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Does longer peripheral intravenous catheter...
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Prestations des soins de santé › Coûts des soins de santé › Does longer peripheral intravenous catheter...
questionsmedicales.fr › Techniques d'investigation › Cathétérisme › Cathétérisme périphérique › Does longer peripheral intravenous catheter...
questionsmedicales.fr › Infection › Infections sur cathéters › Does longer peripheral intravenous catheter...
questionsmedicales.fr › Équipement et fournitures › Cathéters › Does longer peripheral intravenous catheter...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études cliniques comme sujet › Essais cliniques comme sujet › Essais cliniques contrôlés comme sujet › Essais contrôlés randomisés comme sujet › Does longer peripheral intravenous catheter...