Detecting impaired muscle relaxation in myopathies with the use of motor cortical stimulation.


Journal

Neuromuscular disorders : NMD
ISSN: 1873-2364
Titre abrégé: Neuromuscul Disord
Pays: England
ID NLM: 9111470

Informations de publication

Date de publication:
05 2023
Historique:
received: 05 10 2022
revised: 01 03 2023
accepted: 02 03 2023
medline: 2 6 2023
pubmed: 9 4 2023
entrez: 8 4 2023
Statut: ppublish

Résumé

Impaired muscle relaxation is a notable feature in specific myopathies. Transcranial magnetic stimulation (TMS) of the motor cortex can induce muscle relaxation by abruptly halting corticospinal drive. Our aim was to quantify muscle relaxation using TMS in different myopathies with symptoms of muscle stiffness, contractures/cramps, and myalgia and explore the technique's diagnostic potential. In men, normalized peak relaxation rate was lower in Brody disease (n = 4) (-3.5 ± 1.3 s

Identifiants

pubmed: 37030055
pii: S0960-8966(23)00066-4
doi: 10.1016/j.nmd.2023.03.002
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

396-404

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Nens van Alfen performs editorial services for Wiley Publishing Inc; payment goes to their employer.

Auteurs

Joery P Molenaar (JP)

Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Postbox 9101, Nijmegen 6500 HB, the Netherlands; Department of Neurology, Rijnstate, Arnhem, the Netherlands.

Esmee van Kleef (E)

Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Postbox 9101, Nijmegen 6500 HB, the Netherlands.

Elianne van Zandvoort (E)

Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Postbox 9101, Nijmegen 6500 HB, the Netherlands.

Nens van Alfen (N)

Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Postbox 9101, Nijmegen 6500 HB, the Netherlands.

Baziel G van Engelen (BG)

Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Postbox 9101, Nijmegen 6500 HB, the Netherlands.

Nicol C Voermans (NC)

Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Postbox 9101, Nijmegen 6500 HB, the Netherlands.

Jonne Doorduin (J)

Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Postbox 9101, Nijmegen 6500 HB, the Netherlands. Electronic address: Jonne.Doorduin@radboudumc.nl.

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Classifications MeSH