Using digital phenotyping to understand health-related outcomes: A scoping review.

Digital phenotyping Health outcomes Scoping review Smartphones

Journal

International journal of medical informatics
ISSN: 1872-8243
Titre abrégé: Int J Med Inform
Pays: Ireland
ID NLM: 9711057

Informations de publication

Date de publication:
06 2023
Historique:
received: 03 08 2022
revised: 10 02 2023
accepted: 24 03 2023
medline: 25 4 2023
pubmed: 9 4 2023
entrez: 8 4 2023
Statut: ppublish

Résumé

Digital phenotyping may detect changes in health outcomes and potentially lead to proactive measures to mitigate health declines and avoid major medical events. While health-related outcomes have traditionally been acquired through self-report measures, those approaches have numerous limitations, such as recall bias, and social desirability bias. Digital phenotyping may offer a potential solution to these limitations. The purpose of this scoping review was to identify and summarize how passive smartphone data are processed and evaluated analytically, including the relationship between these data and health-related outcomes. A search of PubMed, Scopus, Compendex, and HTA databases was conducted for all articles in April 2021 using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Review (PRISMA-ScR) guidelines. A total of 40 articles were included and went through an analysis based on data collection approaches, feature extraction, data analytics, behavioral markers, and health-related outcomes. This review demonstrated a layer of features derived from raw sensor data that can then be integrated to estimate and predict behaviors, emotions, and health-related outcomes. Most studies collected data from a combination of sensors. GPS was the most used digital phenotyping data. Feature types included physical activity, location, mobility, social activity, sleep, and in-phone activity. Studies involved a broad range of the features used: data preprocessing, analysis approaches, analytic techniques, and algorithms tested. 55% of the studies (n = 22) focused on mental health-related outcomes. This scoping review catalogued in detail the research to date regarding the approaches to using passive smartphone sensor data to derive behavioral markers to correlate with or predict health-related outcomes. Findings will serve as a central resource for researchers to survey the field of research designs and approaches performed to date and move this emerging domain of research forward towards ultimately providing clinical utility in patient care.

Sections du résumé

BACKGROUND
Digital phenotyping may detect changes in health outcomes and potentially lead to proactive measures to mitigate health declines and avoid major medical events. While health-related outcomes have traditionally been acquired through self-report measures, those approaches have numerous limitations, such as recall bias, and social desirability bias. Digital phenotyping may offer a potential solution to these limitations.
OBJECTIVES
The purpose of this scoping review was to identify and summarize how passive smartphone data are processed and evaluated analytically, including the relationship between these data and health-related outcomes.
METHODS
A search of PubMed, Scopus, Compendex, and HTA databases was conducted for all articles in April 2021 using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Review (PRISMA-ScR) guidelines.
RESULTS
A total of 40 articles were included and went through an analysis based on data collection approaches, feature extraction, data analytics, behavioral markers, and health-related outcomes. This review demonstrated a layer of features derived from raw sensor data that can then be integrated to estimate and predict behaviors, emotions, and health-related outcomes. Most studies collected data from a combination of sensors. GPS was the most used digital phenotyping data. Feature types included physical activity, location, mobility, social activity, sleep, and in-phone activity. Studies involved a broad range of the features used: data preprocessing, analysis approaches, analytic techniques, and algorithms tested. 55% of the studies (n = 22) focused on mental health-related outcomes.
CONCLUSION
This scoping review catalogued in detail the research to date regarding the approaches to using passive smartphone sensor data to derive behavioral markers to correlate with or predict health-related outcomes. Findings will serve as a central resource for researchers to survey the field of research designs and approaches performed to date and move this emerging domain of research forward towards ultimately providing clinical utility in patient care.

Identifiants

pubmed: 37030145
pii: S1386-5056(23)00079-5
doi: 10.1016/j.ijmedinf.2023.105061
pii:
doi:

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

105061

Informations de copyright

Copyright © 2023 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Kyungmi Lee (K)

Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, United States. Electronic address: kxl916@case.edu.

Tim Cheongho Lee (TC)

College of Gyedang General Education, Sangmyung University, Seoul, Republic of Korea. Electronic address: tcleethephilosopher@smu.ac.kr.

Maria Yefimova (M)

Health Department of Nursing, University of California San Francisco, San Francisco, CA, United States.

Sidharth Kumar (S)

Department of Computer Science, University of Alabama at Birmingham, Birmingham, AL, United States.

Frank Puga (F)

School of Nursing, University of Alabama at Birmingham, Birmingham, AL, United States.

Andres Azuero (A)

School of Nursing, University of Alabama at Birmingham, Birmingham, AL, United States.

Arif Kamal (A)

Department of Medicine, Duke University School of Medicine, Durham, NC, United States.

Marie A Bakitas (MA)

School of Nursing, University of Alabama at Birmingham, Birmingham, AL, United States; Division of Geriatrics, Gerontology, and Palliative Care, University of Alabama at Birmingham, Department of Medicine, Birmingham, AL, United States; University of Alabama at Birmingham, Center for Palliative and Supportive Care, Birmingham, AL, United States.

Alexi A Wright (AA)

Harvard Medical School, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States.

George Demiris (G)

Department of Biobehavioral and Health Sciences, School of Nursing & Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

Christine S Ritchie (CS)

Division of Palliative Care and Geriatric Medicine and Mongan Institute Center for Aging and Serious Illness, Massachusetts General Hospital, Boston, MA, United States.

Carolyn E Z Pickering (CEZ)

School of Nursing, University of Alabama at Birmingham, Birmingham, AL, United States.

J Nicholas Dionne-Odom (J)

School of Nursing, University of Alabama at Birmingham, Birmingham, AL, United States; Division of Geriatrics, Gerontology, and Palliative Care, University of Alabama at Birmingham, Department of Medicine, Birmingham, AL, United States; University of Alabama at Birmingham, Center for Palliative and Supportive Care, Birmingham, AL, United States.

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Classifications MeSH