Silicon dioxide nanoparticles adsorption alters the secondary and tertiary structures of catalase and undermines its activity.
Antioxidant enzyme
Enzyme activity
Molecular docking
SiO(2) nanoparticles
TiO(2) nanoparticles
Journal
Environmental pollution (Barking, Essex : 1987)
ISSN: 1873-6424
Titre abrégé: Environ Pollut
Pays: England
ID NLM: 8804476
Informations de publication
Date de publication:
01 Jul 2023
01 Jul 2023
Historique:
received:
26
11
2022
revised:
31
03
2023
accepted:
06
04
2023
medline:
9
5
2023
pubmed:
10
4
2023
entrez:
9
4
2023
Statut:
ppublish
Résumé
The expanding production and use of nanomaterials in various fields caused big concern for human health. Oxidative stress is the most frequently described mechanism of nanomaterial toxicity. A state of oxidative stress can be defined as the imbalance of reactive oxygen species (ROS) production and antioxidant enzyme activities. Although nanomaterials-triggered ROS generation has been extensively investigated, little is known regarding the regulation of antioxidant enzyme activities by nanomaterials. This study used two typical nanomaterials, SiO
Identifiants
pubmed: 37031852
pii: S0269-7491(23)00603-6
doi: 10.1016/j.envpol.2023.121601
pii:
doi:
Substances chimiques
Catalase
EC 1.11.1.6
Antioxidants
0
titanium dioxide
15FIX9V2JP
Reactive Oxygen Species
0
Silicon Dioxide
7631-86-9
Titanium
D1JT611TNE
Superoxide Dismutase
EC 1.15.1.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
121601Informations de copyright
Copyright © 2023 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.