Disease Burden of Dysmenorrhea: Impact on Life Course Potential.

adolescents chronic pain health trajectory primary dysmenorrhea women’s health

Journal

International journal of women's health
ISSN: 1179-1411
Titre abrégé: Int J Womens Health
Pays: New Zealand
ID NLM: 101531698

Informations de publication

Date de publication:
2023
Historique:
received: 30 12 2022
accepted: 13 03 2023
medline: 11 4 2023
entrez: 10 4 2023
pubmed: 11 4 2023
Statut: epublish

Résumé

Dysmenorrhea is the most common gynecologic condition among the female population and has a significant impact on life course potential. It has a widespread impact on a female's mental and physical well-being, with longstanding impairments on quality of life, personal relationships, and education and career attainment. Furthermore, untreated dysmenorrhea can lead to hyperalgesic priming, which predisposes to chronic pelvic pain. Primary dysmenorrhea is pain in the lower abdomen that occurs before or during menses and in the absence of pelvic pathology. One possible mechanism is endometrial inflammation and increased prostaglandin release, resulting in painful uterine contractions. Dysmenorrhea may also occur secondary to pelvic pathology, such as endometriosis, adenomyosis or due to cyclic exacerbation of non-gynecologic pain conditions. A thorough patient evaluation is essential to differentiate between potential causes and guide management. Treatment must be tailored to individual patient symptoms. Pharmacologic management with non-steroidal anti-inflammatory medications and/or combined hormonal contraceptives is most common. Heat therapy, exercise, vitamins and dietary supplements have limited evidence and can be offered for patients seeking non-pharmacologic adjunctive or alternative options. Greater awareness for both health-care providers and patients allows for early intervention to reduce impact on quality of life and life course potential.

Identifiants

pubmed: 37033122
doi: 10.2147/IJWH.S380006
pii: 380006
pmc: PMC10081671
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

499-509

Informations de copyright

© 2023 MacGregor et al.

Déclaration de conflit d'intérêts

Dr. Catherine Allaire reports personal fees from Abbvie, personal fees from Ferring, outside the submitted work. Dr. Mohamed Bedaiwy reports financial affiliations with Ferring Pharmaceuticals, AbbVie, and Baxter. Dr Paul J Yong is supported by a Health Professional Investigator Award from Michael Smith Health BC and a Canada Research Chair (Tier 2) in Endometriosis and Pelvic Pain. Dr. Olga Bougie reports financial affiliations with Hologic and AbbVie. Received Grant from SRI-Bayer. The authors report no other conflicts of interest in this work.

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Auteurs

Brittany MacGregor (B)

Department of Obstetrics and Gynaecology, University of British Columbia, BC Women's Centre for Pelvic Pain and Endometriosis, Vancouver, Canada.

Catherine Allaire (C)

Department of Obstetrics and Gynaecology, University of British Columbia, BC Women's Centre for Pelvic Pain and Endometriosis, Vancouver, Canada.

Mohamed A Bedaiwy (MA)

Department of Obstetrics and Gynaecology, University of British Columbia, BC Women's Centre for Pelvic Pain and Endometriosis, Vancouver, Canada.

Paul J Yong (PJ)

Department of Obstetrics and Gynaecology, University of British Columbia, BC Women's Centre for Pelvic Pain and Endometriosis, Vancouver, Canada.

Olga Bougie (O)

Department of Obstetrics and Gynaecology, Queen's University, Kingston, Canada.

Classifications MeSH