Verrucous Granular Parakeratosis on the Groin: A Case Report.

glucocorticoid granular parakeratosis groin papule tretinoin verrucous

Journal

Clinical, cosmetic and investigational dermatology
ISSN: 1178-7015
Titre abrégé: Clin Cosmet Investig Dermatol
Pays: New Zealand
ID NLM: 101543449

Informations de publication

Date de publication:
2023
Historique:
received: 22 02 2023
accepted: 25 03 2023
medline: 11 4 2023
entrez: 10 4 2023
pubmed: 11 4 2023
Statut: epublish

Résumé

Granular parakeratosis is a rare dermatosis characterized by erythematous scaly patches or papules, and plaques, often involving intertriginous areas. In this work, a 73-year-old Chinese male patient presented with a 6-month history of pruritic verrucous papules on the bilateral groin. A skin biopsy was performed and revealed the following: the horny layer showed highly compact hyperkeratosis and parakeratosis with basophilic granules; the epidermis showed obvious acanthosis with psoriasiform hyperplasia. The final diagnosis was verrucous granular parakeratosis. We also reviewed the progress in nomenclature, etiology, clinical manifestations, differential diagnosis and treatment. Different clinical manifestations may represent different clinical entities. Dermatologists should differentiate it from other diseases to make a correct diagnosis. Treatment options should be based on the variable etiologies and clinical manifestations.

Identifiants

pubmed: 37033787
doi: 10.2147/CCID.S401799
pii: 401799
pmc: PMC10076618
doi:

Types de publication

Case Reports

Langues

eng

Pagination

853-857

Informations de copyright

© 2023 Li et al.

Déclaration de conflit d'intérêts

All authors have no conflicts of interest to declare for this work.

Références

Clin Cosmet Investig Dermatol. 2022 Jul 15;15:1367-1370
pubmed: 35874456
J Am Acad Dermatol. 2005 May;52(5):863-7
pubmed: 15858479
Australas J Dermatol. 2022 Aug;63(3):368-371
pubmed: 35535765
J Am Acad Dermatol. 1998 Sep;39(3):495-6
pubmed: 9738790
J Am Acad Dermatol. 2002 Nov;47(5 Suppl):S279-80
pubmed: 12399751
J Cutan Med Surg. 2003 Jul-Aug;7(4):330-2
pubmed: 14738100
Am J Clin Dermatol. 2015 Dec;16(6):495-500
pubmed: 26242230
Clin Exp Dermatol. 2022 Dec;47(12):2196-2200
pubmed: 36164686
Int J Dermatol. 2022 Aug;61(8):973-978
pubmed: 35094385
Australas J Dermatol. 2019 Nov;60(4):311-314
pubmed: 31049927
J Am Acad Dermatol. 1997 Nov;37(5 Pt 1):789-90
pubmed: 9366832
J Am Acad Dermatol. 1991 Apr;24(4):541-4
pubmed: 2033126
J Cutan Pathol. 1999 Aug;26(7):339-52
pubmed: 10487291

Auteurs

Huixian Li (H)

Department of Sterilization Supply, Weifang People's Hospital, Weifang, Shandong, People's Republic of China.

Hui Li (H)

Department of Dermatology, Weifang People's Hospital, Weifang, Shandong, People's Republic of China.

Qinghua Tian (Q)

Department of Dermatology, Weifang People's Hospital, Weifang, Shandong, People's Republic of China.

Xiangang Fang (X)

Department of Dermatology, Weifang People's Hospital, Weifang, Shandong, People's Republic of China.

Classifications MeSH