What is the right moment for noninvasive ventilation in amyotrophic lateral sclerosis?

amyotrophic lateral sclerosis noninvasive ventilation pulmonary function

Journal

Archives of medical science : AMS
ISSN: 1734-1922
Titre abrégé: Arch Med Sci
Pays: Poland
ID NLM: 101258257

Informations de publication

Date de publication:
2023
Historique:
received: 05 04 2019
accepted: 08 09 2019
medline: 8 12 2019
entrez: 10 4 2023
pubmed: 8 12 2019
Statut: epublish

Résumé

The most common cause of death in patients with amyotrophic lateral sclerosis (ALS) is respiratory failure, often in the period of 2-5 years, with a small percentage of patients surviving up to 10 years or more. The aim of the study was to evaluate the significance of pulmonary function tests in prediction of mortality and definition of indications for noninvasive mechanical ventilation (NIMV). This retrospective-prospective study was performed at the Clinic of Pulmonology, Clinical Centre of Serbia in the period from January 2015 to December 2017. Patients with diagnosis of ALS established according to El Escorial criteria were included. The study included 76 patients with ALS, 50 (65.85%) with spinal and 26 (34.2%) with bulbar form of disease. Forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV Our study points to the significance of timely application and early start of NIMV in patients with ALS as an important approach to defer functional impairment, which would mean that the criteria, in our country, for application of these devices must be changed, not only regarding the value of current functional diagnostic tests used in everyday practice in patients with ALS but also in regard to the introduction of new diagnostic tests, such as sniff nasal inspiratory pressure and/or polysomnographic testing.

Identifiants

pubmed: 37034525
doi: 10.5114/aoms.2019.90465
pii: 112212
pmc: PMC10074320
doi:

Types de publication

Journal Article

Langues

eng

Pagination

337-342

Informations de copyright

Copyright: © 2019 Termedia & Banach.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Jovana Maskovic (J)

Clinic of Pulmonology, Clinical Center of Serbia, Belgrade, Serbia.

Aleksandra Ilic (A)

Clinic of Pulmonology, Clinical Center of Serbia, Belgrade, Serbia.
Medical Faculty, University of Belgrade, Belgrade, Serbia.

Vladimir Zugic (V)

Clinic of Pulmonology, Clinical Center of Serbia, Belgrade, Serbia.
Medical Faculty, University of Belgrade, Belgrade, Serbia.

Zorica Stevic (Z)

Medical Faculty, University of Belgrade, Belgrade, Serbia.
Clinic of Neurology, Clinical Center of Serbia, Belgrade, Serbia.

Mihailo I Stjepanovic (MI)

Clinic of Pulmonology, Clinical Center of Serbia, Belgrade, Serbia.
Medical Faculty, University of Belgrade, Belgrade, Serbia.

Classifications MeSH