The dual role of autophagy in periprosthetic osteolysis.
RANKL
aseptic loosening
autophagy
mitophagy
periprosthetic osteolysis
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2023
2023
Historique:
received:
14
12
2022
accepted:
16
03
2023
medline:
11
4
2023
entrez:
10
4
2023
pubmed:
11
4
2023
Statut:
epublish
Résumé
Periprosthetic osteolysis (PPO) induced by wear particles is an important cause of aseptic loosening after artificial joint replacement, among which the imbalance of osteogenesis and osteoclastic processes occupies a central position. The cells involved in PPO mainly include osteoclasts (macrophages), osteoblasts, osteocytes, and fibroblasts. RANKL/RANK/OGP axis is a typical way for osteolysis. Autophagy, a mode of regulatory cell death and maintenance of cellular homeostasis, has a dual role in PPO. Although autophagy is activated in various periprosthetic cells and regulates the release of inflammatory cytokines, osteoclast activation, and osteoblast differentiation, its beneficial or detrimental role remains controversy. In particular, differences in the temporal control and intensity of autophagy may have different effects. This article focuses on the role of autophagy in PPO, and expects the regulation of autophagy to become a powerful target for clinical treatment of PPO.
Identifiants
pubmed: 37035243
doi: 10.3389/fcell.2023.1123753
pii: 1123753
pmc: PMC10080036
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1123753Informations de copyright
Copyright © 2023 Yin, Gong, Wang, Liu, Wang and Yin.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Biomed Mater Res A. 2013 Oct;101(10):3033-45
pubmed: 23568608
Annu Rev Biochem. 2009;78:769-96
pubmed: 19489733
Bone. 1999 Jul;25(1):137-9
pubmed: 10423039
Ann N Y Acad Sci. 2010 Mar;1192:367-75
pubmed: 20392262
Biochem Biophys Res Commun. 2006 Jan 6;339(1):437-42
pubmed: 16300744
Cell Death Differ. 2018 Feb;25(2):229-240
pubmed: 28914882
Acta Biomater. 2017 Oct 15;62:362-371
pubmed: 28867647
Science. 2019 Nov 15;366(6467):818-822
pubmed: 31727826
Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):6031-6
pubmed: 17389386
Genes Dev. 1999 Apr 15;13(8):1015-24
pubmed: 10215628
Cell Biol Int. 2021 Mar;45(3):612-622
pubmed: 33386763
J Clin Invest. 2014 Oct;124(10):4351-62
pubmed: 25157819
Am J Pathol. 1997 Aug;151(2):317-22
pubmed: 9250144
J Cell Mol Med. 2020 Dec;24(24):14366-14380
pubmed: 33135301
Med Sci Monit. 2018 Feb 13;24:903-911
pubmed: 29438359
Biomaterials. 2016 Feb;80:1-10
pubmed: 26695376
Autophagy. 2020 Aug;16(8):1482-1505
pubmed: 31679460
Biochem Pharmacol. 2009 Jun 15;77(12):1757-62
pubmed: 19428330
Biochim Biophys Acta. 2009 Jan;1792(1):3-13
pubmed: 19022377
Rejuvenation Res. 2005 Spring;8(1):3-5
pubmed: 15798367
J Transl Med. 2014 Dec 10;12:330
pubmed: 25491303
Cell Death Dis. 2018 Aug 6;9(8):840
pubmed: 30082761
N Engl J Med. 2000 Aug 24;343(8):522-9
pubmed: 10954759
Bone Joint J. 2013 Aug;95-B(8):1022-6
pubmed: 23908414
Oncogene. 2006 Oct 30;25(51):6680-4
pubmed: 17072321
J Biol Chem. 2020 May 8;295(19):6629-6640
pubmed: 32165499
J Cell Biol. 1962 Jan;12:198-202
pubmed: 13862833
Acta Biomater. 2015 Sep;24:352-60
pubmed: 26112372
J Bone Miner Res. 2005 Jul;20(7):1136-48
pubmed: 15940366
Can J Surg. 2012 Dec;55(6):408-17
pubmed: 22992398
Sci Rep. 2020 Mar 27;10(1):5562
pubmed: 32221318
J Cell Biol. 2003 Jan 20;160(2):189-200
pubmed: 12527753
Acta Orthop Scand. 1993 Oct;64(5):497-506
pubmed: 8237312
Nature. 2019 Apr;568(7753):541-545
pubmed: 30971820
Nanomedicine. 2011 Dec;7(6):975-82
pubmed: 21645642
Sci Rep. 2016 Apr 11;6:24262
pubmed: 27064143
Biomaterials. 2018 Oct;179:29-45
pubmed: 29960822
Biomaterials. 1999 Apr;20(7):625-30
pubmed: 10208404
J Cell Biol. 1967 May;33(2):437-49
pubmed: 4292315
Biomaterials. 2010 Jul;31(19):5045-50
pubmed: 20398931
J Am Acad Orthop Surg. 2008;16 Suppl 1:S42-8
pubmed: 18612013
Lancet. 2007 Oct 27;370(9597):1508-19
pubmed: 17964352
Curr Opin Rheumatol. 2006 Jan;18(1):80-7
pubmed: 16344623
Curr Opin Rheumatol. 2018 Jan;30(1):101-107
pubmed: 28957964
Semin Cancer Biol. 2020 Nov;66:171-181
pubmed: 32201367
Ann Rheum Dis. 1971 Nov;30(6):560-4
pubmed: 5130137
Bioact Mater. 2021 Jan 26;6(8):2372-2389
pubmed: 33553822
Ann Oncol. 2006 Dec;17(12):1854-5
pubmed: 16936183
Expert Rev Mol Med. 2009 Dec 02;11:e36
pubmed: 19951459
Nat Med. 2007 Jul;13(7):791-801
pubmed: 17618270
Cell. 2011 Nov 11;147(4):728-41
pubmed: 22078875
Cell Prolif. 2021 Dec;54(12):e13142
pubmed: 34632658
J Orthop Res. 2006 Mar;24(3):461-73
pubmed: 16450379
J Clin Invest. 2021 Mar 1;131(5):
pubmed: 33645545
Front Immunol. 2017 Feb 27;8:185
pubmed: 28289415
Bone. 2013 Jun;54(2):258-63
pubmed: 22939943
FEBS Lett. 2010 Mar 19;584(6):1073-9
pubmed: 20153330
BMC Complement Altern Med. 2019 Oct 15;19(1):269
pubmed: 31615565
Materials (Basel). 2019 Jun 25;12(12):
pubmed: 31242601
Biomaterials. 2014 Aug;35(24):6299-310
pubmed: 24816285
J Bone Joint Surg Am. 2022 Aug 3;104(15):1334-1340
pubmed: 35930380
PLoS Med. 2019 Jul 2;16(7):e1002847
pubmed: 31265453
Nat Rev Mol Cell Biol. 2018 Jun;19(6):365-381
pubmed: 29626215
Adv Funct Mater. 2014 Jan 29;24(4):472-479
pubmed: 25419210
J Arthroplasty. 2016 Sep;31(9):1959-62
pubmed: 27017204
J Cell Biol. 2008 Dec 1;183(5):795-803
pubmed: 19029340
Osteoarthritis Cartilage. 2014 Mar;22(3):389-406
pubmed: 24389057
Int J Nanomedicine. 2017 Jun 07;12:4323-4333
pubmed: 28652735
Biomater Sci. 2021 Jul 13;9(14):4922-4935
pubmed: 34052845
Front Mol Biosci. 2021 Jun 23;8:666295
pubmed: 34250013
Br J Pharmacol. 2008 Mar;153 Suppl 1:S241-6
pubmed: 17965753
Autophagy. 2007 Jul-Aug;3(4):295-9
pubmed: 17404494
Mitochondrion. 2010 Jun;10(4):309-15
pubmed: 20083234
Autophagy. 2021 Dec;17(12):4266-4285
pubmed: 33843441
Genes Dev. 1997 Dec 15;11(24):3482-96
pubmed: 9407039
J Pathol. 2010 May;221(1):3-12
pubmed: 20225336
IUBMB Life. 2005 Jun;57(6):389-95
pubmed: 16012047
Nat Med. 2011 Sep 11;17(10):1231-4
pubmed: 21909105
Autophagy. 2017 Jan 2;13(1):187-200
pubmed: 27846374
Orthopedics. 2008 Jun;31(6):518, 615-8
pubmed: 18661872
Inflammation. 2020 Apr;43(2):673-685
pubmed: 31845051
Lancet. 2018 Nov 3;392(10158):1672-1682
pubmed: 30496082
Oncogene. 2005 Jun 23;24(27):4421-32
pubmed: 15856026
Autophagy. 2012 Nov;8(11):1577-89
pubmed: 22874567
PLoS Biol. 2010 Jan 26;8(1):e1000298
pubmed: 20126261
Curr Opin Pharmacol. 2013 Jun;13(3):413-9
pubmed: 23562164
Int J Nanomedicine. 2017 May 10;12:3617-3636
pubmed: 28553103
Antioxid Redox Signal. 2014 Jan 20;20(3):460-73
pubmed: 23725295
Biochim Biophys Acta. 2015 Feb;1852(2):277-89
pubmed: 24928309
Acta Biomater. 2017 Feb;49:541-554
pubmed: 27890623
Autophagy. 2016 May 3;12(5):850-63
pubmed: 27002654
Open Biol. 2012 May;2(5):120080
pubmed: 22724072
J Bone Joint Surg Am. 2007 Apr;89(4):780-5
pubmed: 17403800
Mol Med Rep. 2019 Jan;19(1):41-50
pubmed: 30387825
Haematologica. 2021 Mar 01;106(3):795-805
pubmed: 32107334
J Bone Miner Metab. 2005;23 Suppl:11-5
pubmed: 15984408
Iran J Basic Med Sci. 2018 Aug;21(8):806-812
pubmed: 30186567
Cell Metab. 2013 Feb 5;17(2):249-60
pubmed: 23395171
Sci Rep. 2016 Feb 11;6:20909
pubmed: 26864916
Nat Commun. 2019 Jul 31;10(1):3436
pubmed: 31366886
Ann Rheum Dis. 2016 Feb;75(2):449-58
pubmed: 25475114
Crit Rev Eukaryot Gene Expr. 2009;19(1):61-72
pubmed: 19191757
Joint Bone Spine. 2016 May;83(3):276-81
pubmed: 26832190
Ann Hum Genet. 2011 Sep;75(5):569-74
pubmed: 21762117
Mucosal Immunol. 2008 Nov;1 Suppl 1:S54-7
pubmed: 19079232
Int Immunopharmacol. 2022 Jun;107:108699
pubmed: 35305384
J Bone Joint Surg Am. 2002 Mar;84(3):411-9
pubmed: 11886911
Biomed Mater. 2012 Aug;7(4):045019
pubmed: 22740586
Nat Rev Drug Discov. 2012 Sep;11(9):709-30
pubmed: 22935804
Front Immunol. 2019 Jun 19;10:1408
pubmed: 31275328
Acta Biomater. 2014 Jan;10(1):1-10
pubmed: 24090989
Autophagy. 2011 Jul;7(7):673-82
pubmed: 21646866
Int J Biol Sci. 2020 Jul 30;16(14):2675-2691
pubmed: 32792864
Biochem Biophys Res Commun. 2016 Apr 22;473(1):133-139
pubmed: 26996127
ACS Nano. 2014 Jun 24;8(6):5898-910
pubmed: 24806912
J Bone Joint Surg Am. 2009 Jan;91(1):128-33
pubmed: 19122087
Clin Orthop Relat Res. 2007 Jan;454:251-61
pubmed: 16980902
Microbiol Spectr. 2016 Jun;4(3):
pubmed: 27337470
J Clin Invest. 2018 Jun 1;128(6):2376-2388
pubmed: 29708513
Int J Mol Med. 2011 Dec;28(6):1055-63
pubmed: 21850366
Autophagy. 2015;11(12):2358-69
pubmed: 26566231
Lancet Neurol. 2018 Sep;17(9):802-815
pubmed: 30129476
J Bone Joint Surg Br. 2012 Jun;94(6):735-45
pubmed: 22628586
Nat Cell Biol. 2013 Jul;15(7):713-20
pubmed: 23817233
Blood. 2004 Oct 1;104(7):2044-50
pubmed: 15213096
J Exp Med. 1999 Dec 20;190(12):1741-54
pubmed: 10601350
Autophagy. 2017 Feb;13(2):285-301
pubmed: 27929705
J Clin Invest. 2009 Apr;119(4):813-25
pubmed: 19258703
Indian J Orthop. 2021 Jul 27;55(5):1326-1334
pubmed: 34824732
Osteoporos Int. 2013 Sep;24(9):2377-86
pubmed: 23468073
J Biol Chem. 2018 Apr 13;293(15):5414-5424
pubmed: 29247007
J Bone Joint Surg Am. 2019 Mar 6;101(5):466-472
pubmed: 30845042
FEBS J. 2017 Jan;284(2):183-195
pubmed: 27462821
Ann N Y Acad Sci. 2007 Nov;1116:281-90
pubmed: 17646259
Acta Biomater. 2017 Jan 15;48:489-498
pubmed: 27838463
Biomolecules. 2022 Nov 23;12(12):
pubmed: 36551161
Elife. 2020 Mar 23;9:
pubmed: 32202502
Immunol Rev. 2005 Dec;208:19-29
pubmed: 16313338
EMBO J. 2011 Jun 24;30(14):2762-78
pubmed: 21701560
Dan Med J. 2017 Mar;64(3):
pubmed: 28260601
Adv Mater. 2021 Jan;33(3):e2006160
pubmed: 33296121