A hypochlorite-activated strategy for realizing fluorescence turn-on, type I and type II ROS-combined photodynamic tumor ablation.

Mice Animals Hypochlorous Acid Fluorescence Mice, Nude Cell Line, Tumor Photochemotherapy Photosensitizing Agents / therapeutic use Nanoparticles
Aggregation-induced emission Hypochlorite Photodynamic therapy Photosensitizer Turn-on fluorescence

Journal

Biomaterials
ISSN: 1878-5905
Titre abrégé: Biomaterials
Pays: Netherlands
ID NLM: 8100316

Informations de publication

Date de publication:
06 2023
Historique:
received: 01 11 2022
revised: 28 03 2023
accepted: 01 04 2023
medline: 15 5 2023
pubmed: 11 4 2023
entrez: 10 4 2023
Statut: ppublish

Résumé

The combination of cancer cell-activated fluorescence and the advantages of both type I and type II photodynamic therapy (PDT) capabilities to achieve a synergistic therapeutic effect in a complex tumor environment is highly desirable. Herein, we report an approach by means of tumor intracellular hypochlorite (ClO

Identifiants

DOI: 10.1016/j.biomaterials.2023.122108 PMID: 37037180
pubmed: 37037180
pii: S0142-9612(23)00116-3
doi: 10.1016/j.biomaterials.2023.122108
pii:
doi:

Substances chimiques

Hypochlorous Acid 712K4CDC10
Photosensitizing Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

122108

Commentaires et corrections

Type : ErratumIn

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Tonghui Huang (T)

School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.

Heng Ji (H)

School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.

Shirong Yan (S)

School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.

Yifan Zuo (Y)

School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.

Jie Li (J)

School of Medical Imaging, Xuzhou Medical University, Xuzhou, 221004, China.

Jacky W Y Lam (JWY)

The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Department of Chemistry, The Hong Kong University of Science and Technology, Kowloon, Hong Kong, 999077, China.

Cuiping Han (C)

School of Medical Imaging, Xuzhou Medical University, Xuzhou, 221004, China. Electronic address: hancp@xzhumu.edu.cn.

Ben Zhong Tang (BZ)

The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Department of Chemistry, The Hong Kong University of Science and Technology, Kowloon, Hong Kong, 999077, China; School of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen, 518172, China. Electronic address: tangbenz@cuhk.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › A hypochlorite-activated strategy for...
questionsmedicales.fr › Eucaryotes › Animaux › A hypochlorite-activated strategy for...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Acide hypochloreux › A hypochlorite-activated strategy for...
questionsmedicales.fr › Phénomènes physiques › Phénomènes optiques › Fluorescence › A hypochlorite-activated strategy for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souches mutantes de souris › Souris nude › A hypochlorite-activated strategy for...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › A hypochlorite-activated strategy for...
questionsmedicales.fr › Thérapeutique › Photothérapie › Photothérapie dynamique › A hypochlorite-activated strategy for...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Radiosensibilisants › Photosensibilisants › A hypochlorite-activated strategy for...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanoparticules › A hypochlorite-activated strategy for...