Absence of self-reported neuropsychiatric and somatic symptoms after Omicron variant SARS-CoV-2 breakthrough infections.

Long COVID Omicron SARS-CoV-2 breakthrough infection neuropsychiatric deficits

Journal

Brain communications
ISSN: 2632-1297
Titre abrégé: Brain Commun
Pays: England
ID NLM: 101755125

Informations de publication

Date de publication:
2023
Historique:
received: 15 07 2022
revised: 16 11 2022
accepted: 23 03 2023
medline: 12 4 2023
entrez: 11 4 2023
pubmed: 12 4 2023
Statut: epublish

Résumé

Persistent somatic and neuropsychiatric symptoms have been frequently described in patients after infection with severe acute respiratory syndrome coronavirus 2 even after a benign clinical course of the acute infection during the early phases of the coronavirus severe acute respiratory syndrome coronavirus 2 pandemic and are part of Long COVID. The Omicron variant emerged in November 2021 and has rapidly become predominant due to its high infectivity and suboptimal vaccine cross-protection. The frequency of neuropsychiatric post-acute sequelae after infection with the severe acute respiratory syndrome coronavirus 2 Omicron and adequate vaccination status is not known. Here, we aimed to characterize post-acute symptoms in individuals with asymptomatic or mildly symptomatic breakthrough infection with severe acute respiratory syndrome coronavirus 2. These individuals had either proven infection with the Omicron variant (

Identifiants

pubmed: 37038497
doi: 10.1093/braincomms/fcad092
pii: fcad092
pmc: PMC10082557
doi:

Types de publication

Journal Article

Langues

eng

Pagination

fcad092

Informations de copyright

© The Author(s) 2023. Published by Oxford University Press on behalf of the Guarantors of Brain.

Déclaration de conflit d'intérêts

The authors declare no competing interests and no conflict of interest. MAF received honoraria for consultation and travel expenses from Biogen, Merck KGaA, Novartis and Roche unrelated to this work.

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Auteurs

Marcel S Woo (MS)

Institute of Neuroimmunology and Multiple Sclerosis, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.

Christina Mayer (C)

Institute of Neuroimmunology and Multiple Sclerosis, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.

Thomas Theo Brehm (TT)

German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg 20246, Germany.
I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.

Gabriele Andersen (G)

Department of Occupational Safety and Health, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.

Angelika Weigel (A)

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.

Bernd Löwe (B)

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.

Ansgar W Lohse (AW)

German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg 20246, Germany.
I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.

Marylyn M Addo (MM)

German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg 20246, Germany.
I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
Institute for Infection Research and Vaccine Development, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.

Christian Gerloff (C)

Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.

Johannes K M Knobloch (JKM)

German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg 20246, Germany.
Institute of Medical Microbiology, Virology and Hygiene, Department for Infection Prevention and Control, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.

Julian Schulze Zur Wiesch (J)

German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg 20246, Germany.
I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.

Manuel A Friese (MA)

Institute of Neuroimmunology and Multiple Sclerosis, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.

Classifications MeSH