Microbial Indicators of Dental Health, Dysbiosis, and Early Childhood Caries.


Journal

Journal of dental research
ISSN: 1544-0591
Titre abrégé: J Dent Res
Pays: United States
ID NLM: 0354343

Informations de publication

Date de publication:
07 2023
Historique:
medline: 22 6 2023
pubmed: 13 4 2023
entrez: 12 4 2023
Statut: ppublish

Résumé

Dental caries lesions are a clinical manifestation of disease, preceded by microbial dysbiosis, which is poorly characterized and thought to be associated with saccharolytic taxa. Here, we assessed the associations between the oral microbiome of children and various caries risk factors such as demographics and behavioral and clinical data across early childhood and characterized over time the salivary and dental plaque microbiome of children before clinical diagnosis of caries lesions. Children (

Identifiants

pubmed: 37042041
doi: 10.1177/00220345231160756
pmc: PMC10288166
doi:

Substances chimiques

RNA, Ribosomal, 16S 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

759-766

Subventions

Organisme : NIDCR NIH HHS
ID : U01 DE021412
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000006
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000433
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000442
Pays : United States

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Auteurs

D Kahharova (D)

Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

V Y Pappalardo (VY)

Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

M J Buijs (MJ)

Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

R X de Menezes (RX)

Biostatistics Centre, Department of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

M Peters (M)

Department of Cariology, Restorative Sciences and Endodontics, University of Michigan, Ann Arbor, MI, USA.

R Jackson (R)

Department of Cariology, Operative Dentistry and Dental Public Health, Indiana University, Indianapolis, IN, USA.

A T Hara (AT)

Department of Cariology, Operative Dentistry and Dental Public Health, Indiana University, Indianapolis, IN, USA.

G Eckert (G)

Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, IN, USA.

B Katz (B)

Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, IN, USA.

M A Keels (MA)

Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.

S M Levy (SM)

Department of Preventive and Community Dentistry, College of Dentistry and Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, USA.

E Zaura (E)

Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

B W Brandt (BW)

Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

M Fontana (M)

Department of Cariology, Restorative Sciences and Endodontics, University of Michigan, Ann Arbor, MI, USA.

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Classifications MeSH