Blood Cell Biomarkers of Inflammation and Cytokine Levels as Predictors of Response to Biologics in Patients with Psoriasis.
biologics
blood cytokines
neutrophil-to-lymphocyte ratio
predictive biomarkers
psoriasis
response to treatment
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
24 Mar 2023
24 Mar 2023
Historique:
received:
20
02
2023
revised:
15
03
2023
accepted:
21
03
2023
medline:
14
4
2023
entrez:
13
4
2023
pubmed:
14
4
2023
Statut:
epublish
Résumé
For people with psoriasis, biomarkers aiding in the personalization of treatment with biologics are needed. We examined the usefulness of several biomarkers of inflammation in this respect. The neutrophil-to-lymphocyte ratio (NLR), the platelet-to-lymphocyte ratio (PLR), and the systemic immune-inflammation index (SII) were measured in patients with psoriasis initiating TNF-α inhibitors (
Identifiants
pubmed: 37047086
pii: ijms24076111
doi: 10.3390/ijms24076111
pmc: PMC10094459
pii:
doi:
Substances chimiques
Interleukin-17
0
Adalimumab
FYS6T7F842
Cytokines
0
Tumor Necrosis Factor-alpha
0
Biological Products
0
Interleukin-6
0
Biomarkers
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Aage Bang Foundation
Organisme : Ebba Celinders Legat
Organisme : AP Møller Foundation
Organisme : The Danish Psoriasis Foundation
Organisme : LEO Foundation
Organisme : Kong Christian X Foundation
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