The Role of MicroRNA in the Pathogenesis of Diabetic Nephropathy.
biomarkers
diabetes mellitus
diabetic nephropathy
microRNA
oxidative stress
transforming growth factor beta
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
25 Mar 2023
25 Mar 2023
Historique:
received:
27
02
2023
revised:
20
03
2023
accepted:
22
03
2023
medline:
14
4
2023
entrez:
13
4
2023
pubmed:
14
4
2023
Statut:
epublish
Résumé
Diabetic nephropathy is one of the most common and severe complications of diabetes mellitus, affecting one in every five patients suffering from diabetes. Despite extensive research, the exact pathogenesis of diabetic nephropathy is still unclear. Several factors and pathways are known to be involved in the development of the disease, such as reactive oxygen species or the activation of the renin-angiotensin-aldosterone system. The expression of those proteins might be extensively regulated by microRNA. Recent research suggests that in diabetic nephropathy patients, the profile of miRNA is significantly changed. In this review, we focus on the actions of miRNA in various pathways involved in the pathogenesis of diabetic nephropathy and the clinical usage of miRNAs as biomarkers and therapeutic targets.
Identifiants
pubmed: 37047185
pii: ijms24076214
doi: 10.3390/ijms24076214
pmc: PMC10094215
pii:
doi:
Substances chimiques
MicroRNAs
0
Reactive Oxygen Species
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Acta Diabetol. 2013 Dec;50(6):965-9
pubmed: 23797704
J Diabetes Res. 2014;2014:920134
pubmed: 25258717
PLoS One. 2013;8(1):e54662
pubmed: 23358711
J Biol Chem. 2011 Jul 22;286(29):25586-603
pubmed: 21613227
J Am Soc Nephrol. 2009 Dec;20(12):2493-502
pubmed: 19875810
Curr Diabetes Rev. 2014 May;10(3):182-9
pubmed: 24919657
J Nephrol. 2018 Dec;31(6):813-831
pubmed: 30019103
J Renin Angiotensin Aldosterone Syst. 2013 Jun;14(2):97-102
pubmed: 23087255
Biochem Pharmacol. 2018 Sep;155:32-47
pubmed: 29940170
Cell Metab. 2019 Oct 1;30(4):656-673
pubmed: 31447320
Nat Cell Biol. 2009 Jul;11(7):881-9
pubmed: 19543271
J Cell Mol Med. 2019 May;23(5):3417-3428
pubmed: 30784180
Sci Rep. 2016 Feb 03;6:20475
pubmed: 26837280
Curr Pharm Des. 2021;27(6):826-832
pubmed: 33087027
Front Endocrinol (Lausanne). 2020 Aug 28;11:590
pubmed: 32982978
PLoS One. 2013;8(3):e58622
pubmed: 23554908
PLoS One. 2013 Oct 25;8(10):e77468
pubmed: 24204837
Evid Based Complement Alternat Med. 2020 Mar 06;2020:6050874
pubmed: 32215042
Stem Cell Res Ther. 2022 Apr 27;13(1):171
pubmed: 35477552
J Biol Chem. 2013 Aug 2;288(31):22469-80
pubmed: 23788640
Clin Chem. 2010 Nov;56(11):1733-41
pubmed: 20847327
J Am Soc Nephrol. 2016 Aug;27(8):2277-88
pubmed: 26647423
J Nephrol. 2006 Nov-Dec;19(6):751-7
pubmed: 17173248
Diabetologia. 2018 May;61(5):996-1011
pubmed: 29520581
FEBS Lett. 2010 Feb 19;584(4):811-6
pubmed: 20067797
Exp Cell Res. 2018 Mar 1;364(1):5-15
pubmed: 29397070
Kidney Int. 1992 Jan;41(1):107-14
pubmed: 1593845
Am J Physiol Endocrinol Metab. 2018 Jan 1;314(1):E21-E38
pubmed: 28851737
J Biol Chem. 2003 Aug 29;278(35):33492-500
pubmed: 12766172
Mol Ther Nucleic Acids. 2017 Dec 15;9:48-56
pubmed: 29246323
Nat Rev Drug Discov. 2017 Mar;16(3):203-222
pubmed: 28209991
Am J Nephrol. 2011;34(6):549-59
pubmed: 22123611
Mol Cancer. 2010 Sep 02;9:231
pubmed: 20813052
Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3432-7
pubmed: 17360662
Cell Biochem Biophys. 2013 Nov;67(2):537-46
pubmed: 23443810
Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F691-700
pubmed: 23804455
Diabetes. 2011 Jan;60(1):280-7
pubmed: 20952520
PLoS One. 2013 May 22;8(5):e64558
pubmed: 23717629
Nat Struct Mol Biol. 2012 Jun 05;19(6):586-93
pubmed: 22664986
Nat Rev Nephrol. 2011 Oct 18;7(12):684-96
pubmed: 22009250
Sci Rep. 2016 May 17;6:26072
pubmed: 27184517
J Hum Hypertens. 2010 Jan;24(1):1-8
pubmed: 19727125
J Allergy Clin Immunol. 2018 Apr;141(4):1202-1207
pubmed: 29074454
Methods Mol Biol. 2017;1509:1-10
pubmed: 27826912
J Am Soc Nephrol. 2011 Sep;22(9):1668-81
pubmed: 21852586
Mediators Inflamm. 2012;2012:146154
pubmed: 22969168
Nat Genet. 2005 Jul;37(7):766-70
pubmed: 15965474
PLoS One. 2016 Mar 01;11(3):e0150154
pubmed: 26930277
Theranostics. 2021 Jan 1;11(7):3183-3195
pubmed: 33537081
Cell Tissue Res. 2012 Jan;347(1):141-54
pubmed: 22105921
Clin J Am Soc Nephrol. 2017 Dec 7;12(12):2032-2045
pubmed: 28522654
Clin Transl Med. 2021 Jun;11(6):e468
pubmed: 34185424
J Cell Mol Med. 2021 Dec;25(23):10798-10813
pubmed: 31568645
Cell Res. 2008 Oct;18(10):983-4
pubmed: 18833286
World J Diabetes. 2010 Nov 15;1(5):141-5
pubmed: 21537441
Diabetologia. 2014 Aug;57(8):1726-36
pubmed: 24908566
Nephron. 2019;143(1):12-16
pubmed: 30273931
J Am Soc Nephrol. 1999 Apr;10(4):790-5
pubmed: 10203363
Nat Rev Nephrol. 2011 Jun;7(6):327-40
pubmed: 21537349
Biochem Biophys Res Commun. 2016 Mar 18;471(4):582-8
pubmed: 26876575
Semin Nephrol. 2003 Nov;23(6):532-43
pubmed: 14631561
Int Urol Nephrol. 2022 Mar;54(3):575-588
pubmed: 34228259
Ann Clin Biochem. 2021 Mar;58(2):141-148
pubmed: 33302703
Am J Nephrol. 2010;32(6):581-9
pubmed: 21071935
Nephrology (Carlton). 2010 Sep;15(6):599-608
pubmed: 20883280
Front Neurol. 2020 Oct 22;11:558758
pubmed: 33192992
FEBS Lett. 2012 Jan 2;586(1):20-6
pubmed: 21827757
Biomed Res Int. 2021 Jul 8;2021:1497449
pubmed: 34307650
Kidney Int. 2011 Aug;80(4):358-68
pubmed: 21389977
Int J Mol Sci. 2019 Jul 29;20(15):
pubmed: 31362427
Exp Cell Res. 2017 Jan 15;350(2):327-335
pubmed: 27964927
Diabetologia. 2017 Jun;60(6):1114-1125
pubmed: 28364255
Am J Physiol Renal Physiol. 2012 Nov 1;303(9):F1341-52
pubmed: 22896043
BMJ. 2017 Jan 17;356:i6505
pubmed: 28096078
Am J Physiol Cell Physiol. 2017 Oct 1;313(4):C430-C447
pubmed: 28701356
Am J Nephrol. 2009;29(3):244-51
pubmed: 18802326
Nat Rev Genet. 2011 Feb;12(2):99-110
pubmed: 21245828
J Biol Chem. 2010 Oct 29;285(44):34004-15
pubmed: 20713358
Trends Biochem Sci. 2014 Apr;39(4):183-90
pubmed: 24656806
Nat Rev Genet. 2008 Feb;9(2):102-14
pubmed: 18197166
Clin Sci (Lond). 2013 Feb;124(3):139-52
pubmed: 23075333
Biomed Res Int. 2017;2017:7839101
pubmed: 29238721
J Biol Chem. 2011 Apr 1;286(13):11837-48
pubmed: 21310958
Diabetes. 2008 Jun;57(6):1446-54
pubmed: 18511445
Diabetes. 2005 Jul;54(7):1976-84
pubmed: 15983197
J Am Soc Nephrol. 2014 Aug;25(8):1698-709
pubmed: 24578127
Diabetes. 2020 Apr;69(4):749-759
pubmed: 31915154
Sci Rep. 2017 May 24;7(1):2314
pubmed: 28539664
J Diabetes Complications. 2016 Apr;30(3):406-14
pubmed: 26775556
FASEB J. 2018 Jun 22;:fj201800597R
pubmed: 29932869
Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4034-9
pubmed: 16495412
J Diabetes Complications. 2016 Nov - Dec;30(8):1585-1592
pubmed: 27475263
J Diabetes Res. 2018 Apr 3;2018:4728645
pubmed: 29850604
Diabetologia. 2020 Feb;63(2):431-443
pubmed: 31740984
Nephrol Dial Transplant. 2011 Nov;26(11):3794-802
pubmed: 21891774
J Biol Chem. 2010 Jul 23;285(30):23457-65
pubmed: 20501654
FASEB J. 2008 Dec;22(12):4126-35
pubmed: 18716028
Crit Rev Clin Lab Sci. 2020 Nov;57(7):470-483
pubmed: 32306805
J Am Soc Nephrol. 2006 Dec;17(12):3325-35
pubmed: 17082237
Ann Transl Med. 2020 Dec;8(24):1689
pubmed: 33490201
J Am Soc Nephrol. 2012 Feb;23(2):252-65
pubmed: 22095944
Int J Mol Sci. 2020 Sep 28;21(19):
pubmed: 32998457
Cell. 2004 Jan 23;116(2):281-97
pubmed: 14744438
J Autoimmun. 2020 May;109:102438
pubmed: 32184036
J Diabetes Res. 2020 Feb 03;2020:2315607
pubmed: 32090116
PLoS One. 2008;3(11):e3694
pubmed: 19002258
Ann N Y Acad Sci. 2015 Sep;1353:72-88
pubmed: 25877817
Front Physiol. 2015 Mar 19;6:82
pubmed: 25852569
Biomed Pharmacother. 2017 Dec;96:471-479
pubmed: 29031207
Biochem Pharmacol. 2021 Jul;189:114301
pubmed: 33203517
Nat Clin Pract Endocrinol Metab. 2008 Aug;4(8):444-52
pubmed: 18607402
Clin Sci (Lond). 2015 Dec;129(12):1237-49
pubmed: 26415649
Nat Commun. 2019 May 13;10(1):2145
pubmed: 31086184
Mol Ther. 2014 Apr;22(4):842-53
pubmed: 24445937
Diabetologia. 2013 Mar;56(3):663-74
pubmed: 23292313
PLoS One. 2013 Dec 09;8(12):e82607
pubmed: 24349318
Physiol Rev. 2013 Jan;93(1):137-88
pubmed: 23303908
Diabetes. 1995 Oct;44(10):1139-46
pubmed: 7556948
Nat Rev Genet. 2015 Jul;16(7):421-33
pubmed: 26077373