Vagal Nerve Activity and Short-Term Clinical Outcomes after Stroke: What Is Left May Not Be Right.
hemispheric differences
stroke
stroke severity
stroke side
vegal nerve activity
vegal nerve activity (HRV)
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
23 Mar 2023
23 Mar 2023
Historique:
received:
04
02
2023
revised:
13
03
2023
accepted:
21
03
2023
medline:
14
4
2023
entrez:
13
4
2023
pubmed:
14
4
2023
Statut:
epublish
Résumé
Stroke is a leading cause of death worldwide. Multiple factors influence the severity of stroke. Normal functional and biological differences seen between the hemispheres may also be related to stroke severity. In the present study, we examined the differences in the severity of stroke as a function of stroke side, and whether patients' vagal nerve activity moderated such differences. We included 87 patients with an ischemic stroke, whose medical records were retrospectively examined for background information (age, gender), stroke side and severity by NIHSS, length of stay in hospital, inflammation such as C-reactive protein, and vagal nerve activity. The vagal activity was indexed by patients' heart-rate variability (HRV), fluctuations in the intervals between normal heartbeats, derived from patients' ECG. Results revealed that patients with left-side stroke had significantly worse NIHSS scores (10.6) than those with right-sided stroke (7.6,
Identifiants
pubmed: 37048532
pii: jcm12072446
doi: 10.3390/jcm12072446
pmc: PMC10095170
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
J Intern Med. 2009 Jun;265(6):663-79
pubmed: 19493060
Neuropsychologia. 1998 May;36(5):461-8
pubmed: 9699952
J Neuroimmunol. 2011 Dec 15;240-241:1-12
pubmed: 21924504
J Psychosom Res. 2022 Jul;158:110911
pubmed: 35489164
Circ Res. 2017 Feb 3;120(3):472-495
pubmed: 28154098
Front Neurosci. 2022 Apr 07;16:813472
pubmed: 35464311
Stroke. 2015 Jan;46(1):252-4
pubmed: 25492906
Ann Neurol. 2004 Jun;55(6):840-4
pubmed: 15174018
Singapore Med J. 2019 Dec;60(12):616-620
pubmed: 31889205
Curr Opin Neurol. 2009 Feb;22(1):60-8
pubmed: 19155763
J Clin Med. 2022 Oct 08;11(19):
pubmed: 36233794
Science. 2011 Oct 7;334(6052):98-101
pubmed: 21921156
J Cogn Neurosci. 2022 Jul 1;34(8):1355-1375
pubmed: 35640102
J Neurointerv Surg. 2022 Nov;14(11):1145-1150
pubmed: 34876497
J Cardiovasc Electrophysiol. 2005 Aug;16(8):864-9
pubmed: 16101628
Eur Rev Med Pharmacol Sci. 2009 Jul-Aug;13(4):299-307
pubmed: 19694345
Biochem Pharmacol. 1998 Nov 1;56(9):1079-87
pubmed: 9802316
Stroke. 2002 Apr;33(4):954-8
pubmed: 11935043
Auton Neurosci. 2012 Jan 26;166(1-2):96-9
pubmed: 22070982
Stroke. 2011 Nov;42(11):3196-201
pubmed: 21921280
J Stroke Cerebrovasc Dis. 2022 Aug;31(8):106569
pubmed: 35777082
Cortex. 2022 Jun;151:15-29
pubmed: 35378419
Neuropsychology. 2016 Sep;30(6):756-766
pubmed: 26618798
PLoS One. 2021 Oct 28;16(10):e0258841
pubmed: 34710127
Stroke Res Treat. 2018 Nov 27;2018:3238165
pubmed: 30598741
Circ Res. 2022 Feb 18;130(4):512-528
pubmed: 35175851
Arch Phys Med Rehabil. 1998 Mar;79(3):329-35
pubmed: 9523787
Brain Circ. 2017 Jan-Mar;3(1):29-34
pubmed: 30276301
Neurorehabil Neural Repair. 2016 Aug;30(7):676-84
pubmed: 26542082
Ann Noninvasive Electrocardiol. 2011 Apr;16(2):117-22
pubmed: 21496161
Biomark Insights. 2018 Jul 18;13:1177271918786931
pubmed: 30038486