Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study.
Duchenne muscular disease (DMD)
Pompe disease
amyotrophic lateral sclerosis (ALS)
intermittent abdominal pressure ventilation (IAPV)
neuromuscular diseases (NMD)
non-invasive ventilation (NIV)
quality of life
retrospective study
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
23 Mar 2023
23 Mar 2023
Historique:
received:
25
01
2023
revised:
06
03
2023
accepted:
13
03
2023
medline:
14
4
2023
entrez:
13
4
2023
pubmed:
14
4
2023
Statut:
epublish
Résumé
Non-invasive ventilatory support (NVS) is a technique used to reduce respiratory work in neuromuscular diseases, preventing the progression of respiratory failure. NVS is usually administered via a nasal or an oronasal mask, causing discomfort, especially in patients ventilated for more than 16 h/day. Intermittent abdominal pressure ventilation (IAPV) differs completely from conventional NVS and consists of a portable ventilator and a corset with Velcro closures as the interface. In our study, the practicability and efficacy of IAPV were studied in three Italian centers monitoring 28 neuromuscular patients using IAPV who were then retrospectively analyzed. The primary outcomes were an improvement in hypoxemia and the normalization of hypercapnia, and the secondary outcome was an improvement in quality of life. Data were collected at baseline (T0) and after two hours of ventilation (T1), with follow-ups at three months (T2) and six months (T3). Statistical significance was found for PaCO
Identifiants
pubmed: 37048537
pii: jcm12072453
doi: 10.3390/jcm12072453
pmc: PMC10095348
pii:
doi:
Types de publication
Journal Article
Langues
eng
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