Glutathione metabolism is conserved in response to excessive copper exposure between mice liver and Aurelia coerulea polyps.
Aurelia coerulea
Conserved response mechanism
Copper exposure
Glutathione metabolism
Mouse model
Journal
The Science of the total environment
ISSN: 1879-1026
Titre abrégé: Sci Total Environ
Pays: Netherlands
ID NLM: 0330500
Informations de publication
Date de publication:
10 Jul 2023
10 Jul 2023
Historique:
received:
09
12
2022
revised:
23
03
2023
accepted:
04
04
2023
medline:
1
6
2023
pubmed:
14
4
2023
entrez:
13
4
2023
Statut:
ppublish
Résumé
Copper (Cu) is a trace element that is engaged in various routine physiological processes. Excessive copper exposure can cause damage to organisms; however, it is unknown if the mechanisms underlying the response to Cu Aurelia coerulea polyps and mice models were exposed to Cu Excessive Cu Glutathione metabolism is a conserved copper response mechanism in evolutionary distant organisms such as A. coerulea polyps and mice, although mammals have a more complex regulatory network when it comes to copper-induced cell death.
Sections du résumé
BACKGROUND
BACKGROUND
Copper (Cu) is a trace element that is engaged in various routine physiological processes. Excessive copper exposure can cause damage to organisms; however, it is unknown if the mechanisms underlying the response to Cu
METHODS
METHODS
Aurelia coerulea polyps and mice models were exposed to Cu
RESULTS
RESULTS
Excessive Cu
CONCLUSION
CONCLUSIONS
Glutathione metabolism is a conserved copper response mechanism in evolutionary distant organisms such as A. coerulea polyps and mice, although mammals have a more complex regulatory network when it comes to copper-induced cell death.
Identifiants
pubmed: 37054792
pii: S0048-9697(23)02001-6
doi: 10.1016/j.scitotenv.2023.163382
pii:
doi:
Substances chimiques
Copper
789U1901C5
Trace Elements
0
Glutathione
GAN16C9B8O
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
163382Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.