Possibility of uncoupling protein 1 expression in bovine fast-twitch muscle fibers.
beef cattle
fast-twitch muscle
uncoupling protein 1
Journal
The Journal of veterinary medical science
ISSN: 1347-7439
Titre abrégé: J Vet Med Sci
Pays: Japan
ID NLM: 9105360
Informations de publication
Date de publication:
01 Jun 2023
01 Jun 2023
Historique:
medline:
2
6
2023
pubmed:
17
4
2023
entrez:
16
4
2023
Statut:
ppublish
Résumé
Uncoupling protein 1 (UCP1) is responsible for non-shivering thermogenesis in brown/beige adipocytes in humans and rodents. Previously, we showed unexpected expression of UCP1 in bovine skeletal muscles. Here we evaluated Ucp1 mRNA levels in the muscle tissue of Japanese Black steers. Expression of Ucp1 was higher in 30-month-old cattle than in 26-month-old cattle. Levels of myosin heavy chain (Myh)1, an MYH predominantly expressed in fast-twitch muscles, were also significantly higher in cattle aged 30 months. A similar tendency was observed in the expression of other Myhs that are highly expressed in fast-twitch muscles, Myh2 and Myh4. Ucp1 expression was positively correlated with expression of Myh1, Myh2, and Myh4. Our results indicate the possibility of Ucp1 expression in fast-twitch muscle fibers.
Identifiants
pubmed: 37062711
doi: 10.1292/jvms.23-0057
pmc: PMC10315545
doi:
Substances chimiques
Uncoupling Protein 1
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
587-591Références
Nat Med. 2012 Oct;18(10):1575-9
pubmed: 22961106
Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Apr;1867(4):159111
pubmed: 35091115
J Mol Histol. 2011 Jun;42(3):205-15
pubmed: 21509445
J Anim Sci. 2018 Sep 7;96(9):3884-3896
pubmed: 29912360
Nature. 2008 Aug 21;454(7207):1000-4
pubmed: 18719589
J Physiol. 1967 Nov;193(1):45-55
pubmed: 16992287
J Biol Chem. 2002 Nov 8;277(45):43079-88
pubmed: 12221093
Annu Rev Physiol. 2014;76:225-49
pubmed: 24188710
J Biol Chem. 2010 Jul 16;285(29):21961-8
pubmed: 20466728
Cell Biochem Funct. 2021 Jan;39(1):116-125
pubmed: 33006416
J Anim Sci. 2016 Dec;94(12):5097-5104
pubmed: 28046166
Front Physiol. 2019 Apr 30;10:470
pubmed: 31133866
Antioxidants (Basel). 2022 Jul 28;11(8):
pubmed: 36009191
Meat Sci. 2000 Jan;54(1):65-70
pubmed: 22063713
Skelet Muscle. 2015 Jul 15;5:22
pubmed: 26180627
Am J Physiol Endocrinol Metab. 2013 Mar 1;304(5):E495-506
pubmed: 23277187
Physiol Rev. 2004 Jan;84(1):277-359
pubmed: 14715917
Cell Biochem Funct. 2016 Jan;34(1):34-41
pubmed: 26781688
Am J Physiol Cell Physiol. 2006 Mar;290(3):C844-51
pubmed: 16251473
Int J Biochem Cell Biol. 2013 Jan;45(1):81-9
pubmed: 23036787