Bupropion-Induced Delayed Hypersensitivity Serum Sickness-Like Reaction.
adverse drug reaction
antidepressant
bupropion
delayed hypersensitivity
serum sickness-like
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Mar 2023
Mar 2023
Historique:
received:
23
02
2023
accepted:
12
03
2023
medline:
18
4
2023
entrez:
17
4
2023
pubmed:
18
4
2023
Statut:
epublish
Résumé
Bupropion is an antidepressant utilized widely for the treatment of various mood disorders and smoking cessation due to its favorable side effect profile, cost, and response to therapy. While serious adverse reactions are rare, in the decades since its approval by the FDA, multiple cases of serum sickness-like reactions to bupropion have been reported, amongst other adverse drug reactions (ADRs). This report is of the case of a 25-year-old female who developed a serum sickness-like reaction to bupropion 21 days after initiation of treatment. She did not respond to conservative therapy but did respond promptly to oral corticosteroids and discontinuation of bupropion. This case serves to bolster the existing literature surrounding ADRs to bupropion and other antidepressant medications in the categories of systemic and dermatologic manifestations.
Identifiants
pubmed: 37065375
doi: 10.7759/cureus.36158
pmc: PMC10103808
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e36158Informations de copyright
Copyright © 2023, Cartwright et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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