Differential Regulation of Retinoic Acid Metabolism in Fanconi Anemia.
Journal
bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187
Informations de publication
Date de publication:
27 Apr 2023
27 Apr 2023
Historique:
pubmed:
18
4
2023
medline:
18
4
2023
entrez:
17
4
2023
Statut:
epublish
Résumé
Fanconi anemia (FA) is a rare genetic disease characterized by heterogeneous congenital abnormalities and increased risk for bone marrow failure and cancer. FA is caused by mutation of any one of 23 genes, the protein products of which function primarily in the maintenance of genome stability. An important role for the FA proteins in the repair of DNA interstrand crosslinks (ICLs) has been established
Identifiants
pubmed: 37066159
doi: 10.1101/2023.04.06.535759
pmc: PMC10104110
pii:
doi:
Types de publication
Preprint
Langues
eng