ITK signaling regulates a switch between T helper 17 and T regulatory cell lineages via a calcium-mediated pathway.

Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
03 Apr 2023
Historique:
pubmed: 18 4 2023
medline: 18 4 2023
entrez: 17 4 2023
Statut: epublish

Résumé

The balance of pro-inflammatory T helper type 17 (Th17) and anti-inflammatory T regulatory (Treg) cells is crucial in maintaining immune homeostasis in health and disease conditions. Differentiation of naïve CD4

Identifiants

DOI: 10.1101/2023.04.01.535229 PMID: 37066370 PMC: PMC10103963
pubmed: 37066370
doi: 10.1101/2023.04.01.535229
pmc: PMC10103963
pii:
doi:

Types de publication

Preprint

Langues

eng

Déclaration de conflit d'intérêts

Competing interests: AA declares research funding from the 3M Company.

Auteurs

Orchi Anannya (O)

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.

Weishan Huang (W)

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA.

Avery August (A)

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
Cornell Center for Immunology, Cornell University, Ithaca, NY 14853, USA.
Cornell Institute of Host-Microbe Interactions and Defense, Cornell University, Ithaca, NY 14853, USA.
Cornell Center for Health Equity, Cornell University, Ithaca, NY 14853, USA.

Classifications MeSH