Efficacy and safety of embolo-sclerotherapy of arteriovenous malformations with foam sodium tetradecyl sulphate.


Journal

International angiology : a journal of the International Union of Angiology
ISSN: 1827-1839
Titre abrégé: Int Angiol
Pays: Italy
ID NLM: 8402693

Informations de publication

Date de publication:
Jun 2023
Historique:
medline: 26 5 2023
pubmed: 18 4 2023
entrez: 17 4 2023
Statut: ppublish

Résumé

To evaluate the efficacy and safety of embolo-sclerotherapy (EST) particularly with foamed sclerotherapy in the treatment of arteriovenous malformations (AVMs). All patients with AVM who underwent interventional therapy i.e. EST from January 1 A total of 65 patients were included. There was no statistical difference amongst the volume of foam STS 3% or alcohol used across all types of AVM. Overall, majority of patients (86.2%) reported some degree of improvement following interventional therapy. Six (9.2%) patients experienced complications including necrosis and amputation. The proportions of complication were significantly different across the categories (P=0.009). Patients with type III AVM seemed to report more complications than others. Foam sclerotherapy was clinically effective and safe for patients with AVM. This study showed that foam sclerotherapy with STS 3% provided a safe and efficacious alternative sclerosant to ethanol despite it was not often reported to be used to treat AVM. However, a combination of embolic agents is likely required to treat type IV AVMs.

Sections du résumé

BACKGROUND BACKGROUND
To evaluate the efficacy and safety of embolo-sclerotherapy (EST) particularly with foamed sclerotherapy in the treatment of arteriovenous malformations (AVMs).
METHODS METHODS
All patients with AVM who underwent interventional therapy i.e. EST from January 1
RESULTS RESULTS
A total of 65 patients were included. There was no statistical difference amongst the volume of foam STS 3% or alcohol used across all types of AVM. Overall, majority of patients (86.2%) reported some degree of improvement following interventional therapy. Six (9.2%) patients experienced complications including necrosis and amputation. The proportions of complication were significantly different across the categories (P=0.009). Patients with type III AVM seemed to report more complications than others.
CONCLUSIONS CONCLUSIONS
Foam sclerotherapy was clinically effective and safe for patients with AVM. This study showed that foam sclerotherapy with STS 3% provided a safe and efficacious alternative sclerosant to ethanol despite it was not often reported to be used to treat AVM. However, a combination of embolic agents is likely required to treat type IV AVMs.

Identifiants

pubmed: 37067389
pii: S0392-9590.23.04993-3
doi: 10.23736/S0392-9590.23.04993-3
doi:

Substances chimiques

Sodium Tetradecyl Sulfate Q1SUG5KBD6
Sclerosing Solutions 0
Ethanol 3K9958V90M

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

268-275

Auteurs

Calver Pang (C)

Department of Vascular Surgery, Royal Free London NHS Foundation Trust, London, UK.
Division of Surgery and Interventional Science, Department of Surgical Biotechnology, Faculty of Medical Sciences, University College London, London, UK.

Donald R Arasakumar (DR)

Department of Vascular Surgery, Royal Free London NHS Foundation Trust, London, UK.

Nicholas Evans (N)

Department of Vascular Surgery, Royal Free London NHS Foundation Trust, London, UK.

Anthie Papadopoulou (A)

Department of Interventional Radiology, Royal Free London NHS Foundation Trust, London, UK.

Mohamed Khalifa (M)

Department of Interventional Radiology, Royal Free London NHS Foundation Trust, London, UK.

Janice Tsui (J)

Department of Vascular Surgery, Royal Free London NHS Foundation Trust, London, UK.
Division of Surgery and Interventional Science, Department of Surgical Biotechnology, Faculty of Medical Sciences, University College London, London, UK.

George Hamilton (G)

Department of Vascular Surgery, Royal Free London NHS Foundation Trust, London, UK.
Division of Surgery and Interventional Science, Department of Surgical Biotechnology, Faculty of Medical Sciences, University College London, London, UK.

Chung-Sim Lim (CS)

Department of Vascular Surgery, Royal Free London NHS Foundation Trust, London, UK - chunglim@nhs.net.
Division of Surgery and Interventional Science, Department of Surgical Biotechnology, Faculty of Medical Sciences, University College London, London, UK.

Jocelyn Brookes (J)

Department of Vascular Surgery, Royal Free London NHS Foundation Trust, London, UK.
Department of Interventional Radiology, Royal Free London NHS Foundation Trust, London, UK.

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Classifications MeSH