Reading Alterations in Parkinson's Disease Indicate Worse Cognitive Status.
Cognition
Eye‐movements
Fixation duration
Parkinson's Disease
Reading
Journal
Movement disorders clinical practice
ISSN: 2330-1619
Titre abrégé: Mov Disord Clin Pract
Pays: United States
ID NLM: 101630279
Informations de publication
Date de publication:
Apr 2023
Apr 2023
Historique:
received:
14
07
2022
revised:
20
12
2022
accepted:
08
01
2023
medline:
19
4
2023
entrez:
18
4
2023
pubmed:
19
4
2023
Statut:
epublish
Résumé
Reading difficulties are commonly reported in Parkinson's disease (PD). So far, only a few studies have assessed reading in PD, most of them confirming a different pattern in patients compared with healthy populations. Impaired oculomotor control is an early feature of PD. Cognitive deficits, on the other hand, may appear early, but they are most prominent at later stages. Although these two factors are thought to be responsible for the alterations in reading performance, it is unclear how each factor contributes to them. To evaluate eye movements during reading in PD and healthy controls (HCs). Data from 42 HCs (36% men) and 48 patients with PD (67% men) at Hoehn and Yahr stages ≤3 were analyzed. PD participants were further divided into 2 groups based on their Montreal Cognitive Assessment (MoCA) score using a cutoff of ≥26. Eye movements were recorded with Tobii Pro Spectrum, a screen-based eye tracker with a sampling rate of 1200 Hz. PD participants performed fewer fixations per second ( Changes in the reading pattern of PD patients are probably attributed to cognitive rather than pure oculomotor alterations.
Sections du résumé
Background
UNASSIGNED
Reading difficulties are commonly reported in Parkinson's disease (PD). So far, only a few studies have assessed reading in PD, most of them confirming a different pattern in patients compared with healthy populations. Impaired oculomotor control is an early feature of PD. Cognitive deficits, on the other hand, may appear early, but they are most prominent at later stages. Although these two factors are thought to be responsible for the alterations in reading performance, it is unclear how each factor contributes to them.
Objectives
UNASSIGNED
To evaluate eye movements during reading in PD and healthy controls (HCs).
Methods
UNASSIGNED
Data from 42 HCs (36% men) and 48 patients with PD (67% men) at Hoehn and Yahr stages ≤3 were analyzed. PD participants were further divided into 2 groups based on their Montreal Cognitive Assessment (MoCA) score using a cutoff of ≥26. Eye movements were recorded with Tobii Pro Spectrum, a screen-based eye tracker with a sampling rate of 1200 Hz.
Results
UNASSIGNED
PD participants performed fewer fixations per second (
Conclusion
UNASSIGNED
Changes in the reading pattern of PD patients are probably attributed to cognitive rather than pure oculomotor alterations.
Identifiants
pubmed: 37070064
doi: 10.1002/mdc3.13663
pii: MDC313663
pmc: PMC10105091
doi:
Types de publication
Journal Article
Langues
eng
Pagination
579-585Informations de copyright
© 2023 The Authors. Movement Disorders Clinical Practice published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Références
Clin EEG Neurosci. 2008 Oct;39(4):169-74
pubmed: 19044213
J Learn Disabil. 2015 Jul-Aug;48(4):433-45
pubmed: 24153403
Front Hum Neurosci. 2014 Dec 23;8:1024
pubmed: 25566039
J Am Geriatr Soc. 2005 Apr;53(4):695-9
pubmed: 15817019
Neurology. 2010 Nov 9;75(19):1717-25
pubmed: 21060094
Front Aging Neurosci. 2020 May 22;12:120
pubmed: 32528271
Parkinsonism Relat Disord. 2016 Nov;32:130-132
pubmed: 27592009
Neurol Sci. 2021 Mar;42(3):1053-1064
pubmed: 32729012
PLoS One. 2018 Jan 24;13(1):e0191005
pubmed: 29364897
Neuroimage. 2015 Oct 1;119:390-7
pubmed: 26151101
Mov Disord. 2018 Oct;33(10):1661-1662
pubmed: 30298615
Invest Ophthalmol Vis Sci. 2012 Aug 13;53(9):5452-61
pubmed: 22661485
J Fr Ophtalmol. 2018 Oct;41(8):718-724
pubmed: 30150017
Mov Disord. 2015 Oct;30(12):1591-601
pubmed: 26474316
Neuropsychologia. 2012 Dec;50(14):3338-47
pubmed: 23000134
Brain Cogn. 1999 Jul;40(2):387-413
pubmed: 10413567
Neuroophthalmology. 2019 Oct 9;44(2):89-99
pubmed: 32395155
Psychol Bull. 1998 Nov;124(3):372-422
pubmed: 9849112
Parkinsonism Relat Disord. 2011 May;17(4):223-30
pubmed: 20801069
Neurology. 2010 Sep 21;75(12):1062-9
pubmed: 20855849
J Clin Exp Neuropsychol. 2014;36(3):302-16
pubmed: 24580505
Mem Cognit. 2018 Jul;46(5):826-839
pubmed: 29484579